7msf

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{{STRUCTURE_7msf| PDB=7msf | SCENE= }}
{{STRUCTURE_7msf| PDB=7msf | SCENE= }}
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'''MS2 PROTEIN CAPSID/RNA COMPLEX'''
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===MS2 PROTEIN CAPSID/RNA COMPLEX===
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==Overview==
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We have determined the crystal structures, at 2.8 A resolution, of two different RNA aptamers, each bound to MS2 coat protein. One of the aptamers contains a non-Watson-Crick base pair, while the other is missing one of the unpaired adenines that make sequence-specific contacts in the wild-type complex. Despite these differences, the RNA aptamers bind in the same location on the protein as the wild-type translational operator. Comparison of these new structures with other MS2-RNA complexes allows us to refine further the definition of the minimal recognition elements and suggests a possible application of the MS2 system for routine structure determination of small nucleic acid motifs.
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(as it appears on PubMed at http://www.pubmed.gov), where 9808042 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9808042}}
==About this Structure==
==About this Structure==
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[[Category: Rna stem loop]]
[[Category: Rna stem loop]]
[[Category: Rna-protein complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 22:46:42 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 14:42:48 2008''

Revision as of 11:42, 3 July 2008

Image:7msf.png

Template:STRUCTURE 7msf

MS2 PROTEIN CAPSID/RNA COMPLEX

Template:ABSTRACT PUBMED 9808042

About this Structure

7MSF is a Single protein structure of sequence from Enterobacterio phage ms2. Full crystallographic information is available from OCA.

Reference

Crystal structures of a series of RNA aptamers complexed to the same protein target., Rowsell S, Stonehouse NJ, Convery MA, Adams CJ, Ellington AD, Hirao I, Peabody DS, Stockley PG, Phillips SE, Nat Struct Biol. 1998 Nov;5(11):970-5. PMID:9808042

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