1z0t

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[[Image:1z0t.gif|left|200px]]
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{{Seed}}
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{{STRUCTURE_1z0t| PDB=1z0t | SCENE= }}
{{STRUCTURE_1z0t| PDB=1z0t | SCENE= }}
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'''Crystal Structure of A. fulgidus Lon proteolytic domain'''
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===Crystal Structure of A. fulgidus Lon proteolytic domain===
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==Overview==
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Although macromolecular crystallography is rapidly becoming largely routine owing to advances in methods of data collection, structure solution and refinement, difficult cases are still common. To remind structural biologists about the kinds of crystallographic difficulties that might be encountered, case studies of several successfully completed structure determinations that utilized less than perfect crystals are discussed here. The structure of the proteolytic domain of Archaeoglobus fulgidus Lon was solved with crystals that contained superimposed orthorhombic and monoclinic lattices, a case not previously described for proteins. Another hexagonal crystal form of this protein exhibited an unusually high degree of non-isomorphism. Crystals of A. fulgidus Rio1 kinase exhibited both pseudosymmetry and twinning. Ways of identifying the observed phenomena and approaches to solving and refining macromolecular structures when only less than perfect crystals are available are discussed here.
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(as it appears on PubMed at http://www.pubmed.gov), where 15983420 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15983420}}
==About this Structure==
==About this Structure==
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[[Category: B-type lon]]
[[Category: B-type lon]]
[[Category: Catalytic ser-lys dyad]]
[[Category: Catalytic ser-lys dyad]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 17:02:55 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat Jul 5 16:21:59 2008''

Revision as of 13:21, 5 July 2008

Image:1z0t.png

Template:STRUCTURE 1z0t

Crystal Structure of A. fulgidus Lon proteolytic domain

Template:ABSTRACT PUBMED 15983420

About this Structure

1Z0T is a Single protein structure of sequence from Archaeoglobus fulgidus. Full crystallographic information is available from OCA.

Reference

Pathological crystallography: case studies of several unusual macromolecular crystals., Dauter Z, Botos I, LaRonde-LeBlanc N, Wlodawer A, Acta Crystallogr D Biol Crystallogr. 2005 Jul;61(Pt 7):967-75. Epub 2005, Jun 24. PMID:15983420

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