2bt6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2bt6.gif|left|200px]]
+
{{Seed}}
 +
[[Image:2bt6.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2bt6| PDB=2bt6 | SCENE= }}
{{STRUCTURE_2bt6| PDB=2bt6 | SCENE= }}
-
'''RU(BPY)2(MBPY)-MODIFIED BOVINE ADRENODOXIN'''
+
===RU(BPY)2(MBPY)-MODIFIED BOVINE ADRENODOXIN===
-
==Overview==
+
<!--
-
Bovine adrenodoxin (Adx) plays an important role in the electron-transfer process in the mitochondrial steroid hydroxylase system of the bovine adrenal cortex. Using electron paramagnetic resonance (EPR) spectroscopy, we showed that photoreduction of the [2Fe-2S] cluster of Adx via (4'-methyl-2,2'-bipyridine)bis(2,2'-bipyridine)ruthenium(II) [Ru(bpy)2(mbpy)] covalently attached to the protein surface can be used as a new approach to probe the "shuttle" hypothesis for the electron transfer by Adx. The 1.5 A resolution crystal structure of a 1:1 Ru(bpy)2(mbpy)-Adx(1-108) complex reveals the site of modification, Cys95, and allows to predict the possible intramolecular electron-transfer pathways within the complex. Photoreduction of uncoupled Adx, mutant Adx(1-108), and Ru(bpy)2(mbpy)-Adx(1-108) using safranin T as the mediating electron donor suggests that two electrons are transferred from the dye to Adx. The intramolecular photoreduction rate constant for the ruthenated Adx has been determined and is discussed according to the predicted pathways.
+
The line below this paragraph, {{ABSTRACT_PUBMED_16411746}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 16411746 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_16411746}}
==About this Structure==
==About this Structure==
Line 40: Line 44:
[[Category: Mitochondrion]]
[[Category: Mitochondrion]]
[[Category: Transit peptide]]
[[Category: Transit peptide]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 20:45:55 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 6 00:58:01 2008''

Revision as of 21:58, 5 July 2008

Image:2bt6.png

Template:STRUCTURE 2bt6

RU(BPY)2(MBPY)-MODIFIED BOVINE ADRENODOXIN

Template:ABSTRACT PUBMED 16411746

About this Structure

2BT6 is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

Light-induced reduction of bovine adrenodoxin via the covalently bound ruthenium(II) bipyridyl complex: intramolecular electron transfer and crystal structure., Halavaty A, Muller JJ, Contzen J, Jung C, Hannemann F, Bernhardt R, Galander M, Lendzian F, Heinemann U, Biochemistry. 2006 Jan 24;45(3):709-18. PMID:16411746

Page seeded by OCA on Sun Jul 6 00:58:01 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2bt6"
Personal tools