SelB
From Proteopedia
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<scene name='Sandbox_14/1wsu-recognition1/4'>specific hydrogen bonds with the protein and with two bridging water molecules (shown in cyan in the jmol).</scene> | <scene name='Sandbox_14/1wsu-recognition1/4'>specific hydrogen bonds with the protein and with two bridging water molecules (shown in cyan in the jmol).</scene> | ||
The planar base is also sandwiched between | The planar base is also sandwiched between | ||
| - | <scene name='Sandbox_14/1wsu-recognition2/2'>three amino acids</scene>in the protein, which form a tight hydrophobic pocket. This is best seen using a | + | <scene name='Sandbox_14/1wsu-recognition2/2'>three amino acids</scene> in the protein, which form a tight hydrophobic pocket. This is best seen using a |
<scene name='Sandbox_14/1wsu-recognition3/1'>spacefilling diagram.</scene> | <scene name='Sandbox_14/1wsu-recognition3/1'>spacefilling diagram.</scene> | ||
The overall shape of the hairpin is recognized by contacts with several | The overall shape of the hairpin is recognized by contacts with several | ||
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In particular, notice the intimate contact formed by both the charged nitrogen and hydrophobic carbon chain of | In particular, notice the intimate contact formed by both the charged nitrogen and hydrophobic carbon chain of | ||
<scene name='Sandbox_14/1wsu-recognition5/1'>arginine 606.</scene> | <scene name='Sandbox_14/1wsu-recognition5/1'>arginine 606.</scene> | ||
| + | |||
| + | <I>(technical note: if you don't see the hydrogen bonds in the first and fifth links, refresh the page. A problem with jmol causes the hydrogen bonds to be displayed only the first time you click on the link)</I> | ||
Revision as of 15:29, 22 July 2008
Elongation factor SelB uses several methods to recognize the selenocysteine insertion sequence found in messenger RNA. The insertion sequence forms a hairpin loop with an unstacked guanine base in the loop. This guanine forms The planar base is also sandwiched between in the protein, which form a tight hydrophobic pocket. This is best seen using a The overall shape of the hairpin is recognized by contacts with several In particular, notice the intimate contact formed by both the charged nitrogen and hydrophobic carbon chain of
(technical note: if you don't see the hydrogen bonds in the first and fifth links, refresh the page. A problem with jmol causes the hydrogen bonds to be displayed only the first time you click on the link)
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Eran Hodis, David S. Goodsell, Joel L. Sussman, David Canner, Eric Martz, Alexander Berchansky
