2hur

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{{STRUCTURE_2hur| PDB=2hur | SCENE= }}
{{STRUCTURE_2hur| PDB=2hur | SCENE= }}
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'''Escherichia coli nucleoside diphosphate kinase'''
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===Escherichia coli nucleoside diphosphate kinase===
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==Overview==
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Nucleoside diphosphate kinase (NDPK) catalyzes the transfer of gamma-phosphate from nucleoside triphosphates to nucleoside diphosphates. The subunit folding and the dimeric basic structural unit are remarkably the same for available structures but, depending on species, dimers self-associate to form hexamers or tetramers. The crystal structure of the Escherichia coli NDPK reveals a new tetrameric quaternary structure for this protein family. The two tetramers differ by the relative orientation of interacting dimers, which face either the convex or the concave side of their central sheet as in either Myxococcus xanthus (type I) or E. coli (type II), respectively. In the type II tetramer, the subunits interact by a new interface harboring a zone called the Kpn loop as in hexamers, but by the opposite face of this loop. The evolutionary conservation of the interface residues indicates that this new quaternary structure seems to be the most frequent assembly mode in bacterial tetrameric NDP kinases.
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(as it appears on PubMed at http://www.pubmed.gov), where 17330300 is the PubMed ID number.
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{{ABSTRACT_PUBMED_17330300}}
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
The structure of the Escherichia coli nucleoside diphosphate kinase reveals a new quaternary architecture for this enzyme family., Moynie L, Giraud MF, Georgescauld F, Lascu I, Dautant A, Proteins. 2007 May 15;67(3):755-65. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17330300 17330300]
The structure of the Escherichia coli nucleoside diphosphate kinase reveals a new quaternary architecture for this enzyme family., Moynie L, Giraud MF, Georgescauld F, Lascu I, Dautant A, Proteins. 2007 May 15;67(3):755-65. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17330300 17330300]
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Nucleoside diphosphate kinase from Escherichia coli., Almaula N, Lu Q, Delgado J, Belkin S, Inouye M, J Bacteriol. 1995 May;177(9):2524-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7730286 7730286]
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Crystal structure of Myxococcus xanthus nucleoside diphosphate kinase and its interaction with a nucleotide substrate at 2.0 A resolution., Williams RL, Oren DA, Munoz-Dorado J, Inouye S, Inouye M, Arnold E, J Mol Biol. 1993 Dec 20;234(4):1230-47. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8263923 8263923]
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Refined X-ray structure of Dictyostelium discoideum nucleoside diphosphate kinase at 1.8 A resolution., Morera S, LeBras G, Lascu I, Lacombe ML, Veron M, Janin J, J Mol Biol. 1994 Nov 11;243(5):873-90. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7966307 7966307]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Nucleoside-diphosphate kinase]]
[[Category: Nucleoside-diphosphate kinase]]
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[[Category: Moynie, L.]]
[[Category: Moynie, L.]]
[[Category: Type ii tetramer]]
[[Category: Type ii tetramer]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 06:44:09 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 13:07:58 2008''

Revision as of 10:08, 27 July 2008

Image:2hur.png

Template:STRUCTURE 2hur

Escherichia coli nucleoside diphosphate kinase

Template:ABSTRACT PUBMED 17330300

About this Structure

2HUR is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

The structure of the Escherichia coli nucleoside diphosphate kinase reveals a new quaternary architecture for this enzyme family., Moynie L, Giraud MF, Georgescauld F, Lascu I, Dautant A, Proteins. 2007 May 15;67(3):755-65. PMID:17330300

Nucleoside diphosphate kinase from Escherichia coli., Almaula N, Lu Q, Delgado J, Belkin S, Inouye M, J Bacteriol. 1995 May;177(9):2524-9. PMID:7730286

Crystal structure of Myxococcus xanthus nucleoside diphosphate kinase and its interaction with a nucleotide substrate at 2.0 A resolution., Williams RL, Oren DA, Munoz-Dorado J, Inouye S, Inouye M, Arnold E, J Mol Biol. 1993 Dec 20;234(4):1230-47. PMID:8263923

Refined X-ray structure of Dictyostelium discoideum nucleoside diphosphate kinase at 1.8 A resolution., Morera S, LeBras G, Lascu I, Lacombe ML, Veron M, Janin J, J Mol Biol. 1994 Nov 11;243(5):873-90. PMID:7966307

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