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1sac

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{{STRUCTURE_1sac| PDB=1sac | SCENE= }}
{{STRUCTURE_1sac| PDB=1sac | SCENE= }}
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'''THE STRUCTURE OF PENTAMERIC HUMAN SERUM AMYLOID P COMPONENT'''
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===THE STRUCTURE OF PENTAMERIC HUMAN SERUM AMYLOID P COMPONENT===
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==Overview==
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The three-dimensional structure of pentameric human serum amyloid P component at high resolution, the first reported for a pentraxin, reveals that the tertiary fold is remarkably similar to that of the legume lectins. Carboxylate and phosphate compounds bind directly to two calcium ions; interactions with a carboxyethylidene ring are mediated by Asn 59 and Gln 148 ligands of the calcium ions. These X-ray results indicate the probable modes of binding of the biologically important ligands, DNA and amyloid fibrils.
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The line below this paragraph, {{ABSTRACT_PUBMED_8114934}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 8114934 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8114934}}
==About this Structure==
==About this Structure==
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[[Category: Wood, S P.]]
[[Category: Wood, S P.]]
[[Category: Amyloid protein]]
[[Category: Amyloid protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 08:28:57 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 13:32:48 2008''

Revision as of 10:32, 27 July 2008

Image:1sac.png

Template:STRUCTURE 1sac

THE STRUCTURE OF PENTAMERIC HUMAN SERUM AMYLOID P COMPONENT

Template:ABSTRACT PUBMED 8114934

About this Structure

1SAC is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Structure of pentameric human serum amyloid P component., Emsley J, White HE, O'Hara BP, Oliva G, Srinivasan N, Tickle IJ, Blundell TL, Pepys MB, Wood SP, Nature. 1994 Jan 27;367(6461):338-45. PMID:8114934

Page seeded by OCA on Sun Jul 27 13:32:48 2008

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