2jhc

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(New page: 200px<br /> <applet load="2jhc" size="450" color="white" frame="true" align="right" spinBox="true" caption="2jhc, resolution 3.00&Aring;" /> '''THE STRUCTURE OF BL...)
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Revision as of 18:05, 29 October 2007

Image:2jhc.gif

2jhc, resolution 3.00Å

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THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE

Overview

Eukaryotic organisms cap the 5' ends of their messenger RNAs by a series, of four chemical reactions. Some viruses achieve this using a single, molecule; the crystal structure of such an enzyme from bluetongue virus, reveals an elongated modular architecture that provides a scaffold for an, assemblage of active sites, two contributed by a domain of novel, structure.

About this Structure

2JHC is a [Single protein] structure of sequence from [Bluetongue virus 10 (isolate usa)] with GUN as [ligand]. Full crystallographic information is available from [OCA].

Reference

Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:17417654

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