1mwg

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1mwg.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1mwg.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1mwg| PDB=1mwg | SCENE= }}
{{STRUCTURE_1mwg| PDB=1mwg | SCENE= }}
-
'''STRUCTURE OF RIBONUCLEIC ACID, NMR, MINIMIZED AVERAGE STRUCTURE'''
+
===STRUCTURE OF RIBONUCLEIC ACID, NMR, MINIMIZED AVERAGE STRUCTURE===
-
==Overview==
+
<!--
-
The three-dimensional solution structure of the RNA self-complementary duplex [sequence: see text] was derived from two-dimensional NMR and the iterative relaxation matrix approach. Each GA mismatch forms two hydrogen bonds: A-NH6 to G-O6 and A-N1 to G-NH1 (imino). This is the first three-dimensional RNA structure with imino hydrogen-bonded tandem GA mismatches. This GA structure is totally different from the sheared tandem GA structure in [sequence: see text] which also has two hydrogen bonds: A-N7 to G-NH2 and A-NH6 to G-N3 [SantaLucia, J., Jr., &amp; Turner, D. H. (1993) Biochemistry 32, 12612-12623]. In particular, the sheared and imino GA mismatches produce a narrowing and widening of the backbone, respectively. The results show that substitutions of Watson-Crick base pairs can have dramatic effects on the three-dimensional structures of adjacent non-Watson-Crick paired regions; i.e., the structure depends on sequence context. Thus compensating substitutions in site-directed mutagenesis experiments may not always restore biological activities.
+
The line below this paragraph, {{ABSTRACT_PUBMED_8703939}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 8703939 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_8703939}}
==About this Structure==
==About this Structure==
-
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MWG OCA].
+
Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MWG OCA].
==Reference==
==Reference==
Line 26: Line 30:
[[Category: G:a mismatch]]
[[Category: G:a mismatch]]
[[Category: Ribonucleic acid]]
[[Category: Ribonucleic acid]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 01:48:07 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 15:01:45 2008''

Revision as of 12:02, 27 July 2008

Image:1mwg.png

Template:STRUCTURE 1mwg

STRUCTURE OF RIBONUCLEIC ACID, NMR, MINIMIZED AVERAGE STRUCTURE

Template:ABSTRACT PUBMED 8703939

About this Structure

Full experimental information is available from OCA.

Reference

Solution structure of (rGCGGACGC)2 by two-dimensional NMR and the iterative relaxation matrix approach., Wu M, Turner DH, Biochemistry. 1996 Jul 30;35(30):9677-89. PMID:8703939

Page seeded by OCA on Sun Jul 27 15:01:45 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1mwg"
Personal tools