1qjp

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{{STRUCTURE_1qjp| PDB=1qjp | SCENE= }}
{{STRUCTURE_1qjp| PDB=1qjp | SCENE= }}
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'''HIGH RESOLUTION STRUCTURE OF THE OUTER MEMBRANE PROTEIN A (OMPA) TRANSMEMBRANE DOMAIN'''
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===HIGH RESOLUTION STRUCTURE OF THE OUTER MEMBRANE PROTEIN A (OMPA) TRANSMEMBRANE DOMAIN===
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==Overview==
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The membrane domain of OmpA consists of an eight-stranded all-next-neighbor antiparallel beta-barrel with short turns at the periplasmic barrel end and long flexible loops at the external end. The structure analysis has been extended from medium resolution to 1. 65 A (1 A=0.1 nm), and the molecular model has been refined anisotropically to show oriented mobilities of the structural elements. The improved data allowed us to locate five further detergent molecules and 11 more water molecules. Moreover, the two large non-polar packing contacts have now been defined in detail. The analysis indicates that the beta-barrel constitutes a solid scaffold such that the long external loops need not contribute to stability. These loops are highly mobile and thus cause a major problem during the crystallization process. The beta-barrel was related to those of lipocalins. Two further crystal forms with exceptionally dense packing arrangements were established at medium resolution.
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The line below this paragraph, {{ABSTRACT_PUBMED_10764596}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 10764596 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10764596}}
==About this Structure==
==About this Structure==
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[[Category: Schulz, G E.]]
[[Category: Schulz, G E.]]
[[Category: Outer membrane]]
[[Category: Outer membrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 06:21:22 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 15:37:29 2008''

Revision as of 12:37, 27 July 2008

Image:1qjp.png

Template:STRUCTURE 1qjp

HIGH RESOLUTION STRUCTURE OF THE OUTER MEMBRANE PROTEIN A (OMPA) TRANSMEMBRANE DOMAIN

Template:ABSTRACT PUBMED 10764596

About this Structure

1QJP is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

High-resolution structure of the OmpA membrane domain., Pautsch A, Schulz GE, J Mol Biol. 2000 Apr 28;298(2):273-82. PMID:10764596

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