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1pbo

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[[Image:1pbo.jpg|left|200px]]
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{{STRUCTURE_1pbo| PDB=1pbo | SCENE= }}
{{STRUCTURE_1pbo| PDB=1pbo | SCENE= }}
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'''COMPLEX OF BOVINE ODORANT BINDING PROTEIN (OBP) WITH A SELENIUM CONTAINING ODORANT'''
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===COMPLEX OF BOVINE ODORANT BINDING PROTEIN (OBP) WITH A SELENIUM CONTAINING ODORANT===
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==Overview==
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Odorant binding protein (OBP) is the major odorant binding component of mammalian nasal mucosa. The two structures of bovine OBP reported in this paper (one crystallized as purified and one soaked in the presence of a selenium-containing odorant) show that: (i) the OBP dimer is composed of two compact domains related by an approximate two-fold axis of symmetry; (ii) between residues 122 and 123 the polypeptide chains cross from one domain to the other such that each domain is formed by residues from both monomers; (iii) purified OBP already contains two bound odorant molecules (one per monomer)-odorant binding occurs by replacement of these molecules with the added odorant; and (iv) the structure of the odorant binding site can explain OBP's extraordinarily broad odorant specificity.
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(as it appears on PubMed at http://www.pubmed.gov), where 8901871 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8901871}}
==About this Structure==
==About this Structure==
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[[Category: Odorant-binding]]
[[Category: Odorant-binding]]
[[Category: Transport]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 04:54:52 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 15:42:09 2008''

Revision as of 12:42, 27 July 2008

Image:1pbo.png

Template:STRUCTURE 1pbo

COMPLEX OF BOVINE ODORANT BINDING PROTEIN (OBP) WITH A SELENIUM CONTAINING ODORANT

Template:ABSTRACT PUBMED 8901871

About this Structure

1PBO is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

The three-dimensional structure of bovine odorant binding protein and its mechanism of odor recognition., Bianchet MA, Bains G, Pelosi P, Pevsner J, Snyder SH, Monaco HL, Amzel LM, Nat Struct Biol. 1996 Nov;3(11):934-9. PMID:8901871

Page seeded by OCA on Sun Jul 27 15:42:09 2008

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