2gat

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{{STRUCTURE_2gat| PDB=2gat | SCENE= }}
{{STRUCTURE_2gat| PDB=2gat | SCENE= }}
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'''SOLUTION STRUCTURE OF THE C-TERMINAL DOMAIN OF CHICKEN GATA-1 BOUND TO DNA, NMR, REGULARIZED MEAN STRUCTURE'''
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===SOLUTION STRUCTURE OF THE C-TERMINAL DOMAIN OF CHICKEN GATA-1 BOUND TO DNA, NMR, REGULARIZED MEAN STRUCTURE===
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==Overview==
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Anisotropy of the molecular magnetic susceptibility gives rise to a small degree of alignment. The resulting residual dipolar couplings, which can now be measured with the advent of higher magnetic fields in NMR, contain information on the orientation of the internuclear vectors relative to the molecular magnetic susceptibility tensor, thereby providing information on long range order that is not accessible by any of the solution NMR parameters currently used in structure determination. Thus, the dipolar couplings constitute unique and powerful restraints in determining the structures of magnetically oriented macromolecules in solution. The method is demonstrated on a complex of the DNA-binding domain of the transcription factor GATA-1 with a 16 base pair oligodeoxyribonucleotide.
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{{ABSTRACT_PUBMED_9303001}}
==About this Structure==
==About this Structure==
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2GAT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GAT OCA].
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2GAT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GAT OCA].
==Reference==
==Reference==
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[[Category: Transcription factor]]
[[Category: Transcription factor]]
[[Category: Zinc binding domain]]
[[Category: Zinc binding domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 04:53:54 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 15:57:05 2008''

Revision as of 12:57, 27 July 2008

Template:STRUCTURE 2gat

SOLUTION STRUCTURE OF THE C-TERMINAL DOMAIN OF CHICKEN GATA-1 BOUND TO DNA, NMR, REGULARIZED MEAN STRUCTURE

Template:ABSTRACT PUBMED 9303001

About this Structure

2GAT is a Single protein structure of sequence from Gallus gallus. Full experimental information is available from OCA.

Reference

Use of dipolar 1H-15N and 1H-13C couplings in the structure determination of magnetically oriented macromolecules in solution., Tjandra N, Omichinski JG, Gronenborn AM, Clore GM, Bax A, Nat Struct Biol. 1997 Sep;4(9):732-8. PMID:9303001

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