1n2d

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[[Image:1n2d.gif|left|200px]]
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{{STRUCTURE_1n2d| PDB=1n2d | SCENE= }}
{{STRUCTURE_1n2d| PDB=1n2d | SCENE= }}
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'''Ternary complex of MLC1P bound to IQ2 and IQ3 of Myo2p, a class V myosin'''
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===Ternary complex of MLC1P bound to IQ2 and IQ3 of Myo2p, a class V myosin===
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==Overview==
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Mlc1p is a calmodulin-like protein from the budding yeast Saccharomyces cerevisiae, where it has been identified as a subunit of a class V myosin, Myo2p, and a binding partner of an IQGAP-like protein, Iqg1p. Through its interactions with these two proteins, Mlc1p plays a role in polarized growth and cytokinesis. Mlc1p has been crystallized in complexes with four different IQ target motifs from the neck region of Myo2p: IQ2, IQ3, IQ4 and IQ2-IQ3 (referred to as IQ2,3). Electron-density maps for two of the complexes (Mlc1p-IQ4 and Mlc1p-IQ2,3) were obtained from multiple anomalous dispersion (MAD) experiments based on selenomethionine derivatives. The other two structures (Mlc1p-IQ2 and Mlc1p-IQ3) were determined by molecular replacement using the partially refined structure of Mlc1p-IQ2,3 as a search model.
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(as it appears on PubMed at http://www.pubmed.gov), where 12351846 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12351846}}
==About this Structure==
==About this Structure==
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[[Category: Myosin light chain]]
[[Category: Myosin light chain]]
[[Category: Protein-peptide complex]]
[[Category: Protein-peptide complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:00:16 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 16:11:27 2008''

Revision as of 13:11, 27 July 2008

Template:STRUCTURE 1n2d

Ternary complex of MLC1P bound to IQ2 and IQ3 of Myo2p, a class V myosin

Template:ABSTRACT PUBMED 12351846

About this Structure

1N2D is a Protein complex structure of sequences from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

Crystallization, X-ray characterization and selenomethionine phasing of Mlc1p bound to IQ motifs from myosin V., Terrak M, Otterbein LR, Wu G, Palecanda LA, Lu RC, Dominguez R, Acta Crystallogr D Biol Crystallogr. 2002 Oct;58(Pt 10 Pt 2):1882-5. Epub, 2002 Sep 28. PMID:12351846

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