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1pil

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{{STRUCTURE_1pil| PDB=1pil | SCENE= }}
{{STRUCTURE_1pil| PDB=1pil | SCENE= }}
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'''STRUCTURE OF THE ESCHERICHIA COLI SIGNAL TRANSDUCING PROTEIN PII'''
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===STRUCTURE OF THE ESCHERICHIA COLI SIGNAL TRANSDUCING PROTEIN PII===
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==Overview==
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BACKGROUND: In Gram-negative proteobacteria, the nitrogen level in the cell is reflected by the uridylylation status of a key signal transducing protein, PII. PII modulates the activity of glutamine synthetase (GS) through its interaction with adenylyl transferase and it represses the expression of GS by acting in concert with nitrogen regulatory protein II. RESULTS: The three-dimensional structure of the Escherichia coli PII trimer has been determined at 2.7 A resolution. PII shows a low level of structural similarity to a broad family of alpha/beta proteins and contains a double beta alpha beta motif. The PII trimer contains three beta-sheets, each of which is composed of strands from each of the three monomers. These are surrounded by six alpha-helices. CONCLUSIONS: The structure of PII suggests potential regions of interaction with other proteins and serves as an initial step in understanding its signal transducing role in nitrogen regulation.
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The line below this paragraph, {{ABSTRACT_PUBMED_7866749}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 7866749 is the PubMed ID number.
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{{ABSTRACT_PUBMED_7866749}}
==About this Structure==
==About this Structure==
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[[Category: Suffolk, P M.]]
[[Category: Suffolk, P M.]]
[[Category: Nitrogen regulatory protein]]
[[Category: Nitrogen regulatory protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 05:07:24 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 16:19:48 2008''

Revision as of 13:19, 27 July 2008

Image:1pil.png

Template:STRUCTURE 1pil

STRUCTURE OF THE ESCHERICHIA COLI SIGNAL TRANSDUCING PROTEIN PII

Template:ABSTRACT PUBMED 7866749

About this Structure

1PIL is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Structure of the Escherichia coli signal transducing protein PII., Cheah E, Carr PD, Suffolk PM, Vasudevan SG, Dixon NE, Ollis DL, Structure. 1994 Oct 15;2(10):981-90. PMID:7866749

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