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1qy6

From Proteopedia

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[[Image:1qy6.jpg|left|200px]]
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{{STRUCTURE_1qy6| PDB=1qy6 | SCENE= }}
{{STRUCTURE_1qy6| PDB=1qy6 | SCENE= }}
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'''Structue of V8 Protease from Staphylococcus aureus'''
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===Structue of V8 Protease from Staphylococcus aureus===
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==Overview==
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V8 protease, an extracellular protease of Staphylococcus aureus, is related to the pancreatic serine proteases. The enzyme cleaves peptide bonds exclusively on the carbonyl side of aspartate and glutamate residues. Unlike the pancreatic serine proteases, V8 protease possesses no disulfide bridges. This is a major evolutionary difference, as all pancreatic proteases have at least two disulfide bridges. The structure of V8 protease shows structural similarity with several other serine proteases, specifically the epidermolytic toxins A and B from S. aureus and trypsin, in which the conformation of the active site is almost identical. V8 protease is also unique in that the positively charged N-terminus is involved in determining the substrate-specificity of the enzyme.
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(as it appears on PubMed at http://www.pubmed.gov), where 14747701 is the PubMed ID number.
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{{ABSTRACT_PUBMED_14747701}}
==About this Structure==
==About this Structure==
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[[Category: Prasad, L.]]
[[Category: Prasad, L.]]
[[Category: Serine protease]]
[[Category: Serine protease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 06:50:44 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 16:36:47 2008''

Revision as of 13:36, 27 July 2008

Image:1qy6.png

Template:STRUCTURE 1qy6

Structue of V8 Protease from Staphylococcus aureus

Template:ABSTRACT PUBMED 14747701

About this Structure

1QY6 is a Single protein structure of sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.

Reference

The structure of a universally employed enzyme: V8 protease from Staphylococcus aureus., Prasad L, Leduc Y, Hayakawa K, Delbaere LT, Acta Crystallogr D Biol Crystallogr. 2004 Feb;60(Pt 2):256-9. Epub 2004, Jan 23. PMID:14747701

Page seeded by OCA on Sun Jul 27 16:36:47 2008

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