1nkw

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{{STRUCTURE_1nkw| PDB=1nkw | SCENE= }}
{{STRUCTURE_1nkw| PDB=1nkw | SCENE= }}
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'''Crystal Structure Of The Large Ribosomal Subunit From Deinococcus Radiodurans'''
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===Crystal Structure Of The Large Ribosomal Subunit From Deinococcus Radiodurans===
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==Overview==
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We describe the high resolution structure of the large ribosomal subunit from Deinococcus radiodurans (D50S), a gram-positive mesophile suitable for binding of antibiotics and functionally relevant ligands. The over-all structure of D50S is similar to that from the archae bacterium Haloarcula marismortui (H50S); however, a detailed comparison revealed significant differences, for example, in the orientation of nucleotides in peptidyl transferase center and in the structures of many ribosomal proteins. Analysis of ribosomal features involved in dynamic aspects of protein biosynthesis that are partially or fully disordered in H50S revealed the conformations of intersubunit bridges in unbound subunits, suggesting how they may change upon subunit association and how movements of the L1-stalk may facilitate the exit of tRNA.
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{{ABSTRACT_PUBMED_11733066}}
==About this Structure==
==About this Structure==
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[[Category: Ribosome]]
[[Category: Ribosome]]
[[Category: X-ray structure]]
[[Category: X-ray structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:39:15 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 17:23:37 2008''

Revision as of 14:23, 27 July 2008

Template:STRUCTURE 1nkw

Crystal Structure Of The Large Ribosomal Subunit From Deinococcus Radiodurans

Template:ABSTRACT PUBMED 11733066

About this Structure

1NKW is a Protein complex structure of sequences from Deinococcus radiodurans. This structure supersedes the now removed PDB entries and 1kc9. Full crystallographic information is available from OCA.

Reference

High resolution structure of the large ribosomal subunit from a mesophilic eubacterium., Harms J, Schluenzen F, Zarivach R, Bashan A, Gat S, Agmon I, Bartels H, Franceschi F, Yonath A, Cell. 2001 Nov 30;107(5):679-88. PMID:11733066

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