1zxk

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1zxk.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1zxk.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1zxk| PDB=1zxk | SCENE= }}
{{STRUCTURE_1zxk| PDB=1zxk | SCENE= }}
-
'''Crystal Structure of Cadherin8 EC1 domain'''
+
===Crystal Structure of Cadherin8 EC1 domain===
-
==Overview==
+
<!--
-
Type I and II classical cadherins help to determine the adhesive specificities of animal cells. Crystal-structure determination of ectodomain regions from three type II cadherins reveals adhesive dimers formed by exchange of N-terminal beta strands between partner extracellular cadherin-1 (EC1) domains. These interfaces have two conserved tryptophan side chains that anchor each swapped strand, compared with one in type I cadherins, and include large hydrophobic regions unique to type II interfaces. The EC1 domains of type I and type II cadherins appear to encode cell adhesive specificity in vitro. Moreover, perturbation of motor neuron segregation with chimeric cadherins depends on EC1 domain identity, suggesting that this region, which includes the structurally defined adhesive interface, encodes type II cadherin functional specificity in vivo.
+
The line below this paragraph, {{ABSTRACT_PUBMED_16564015}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 16564015 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_16564015}}
==About this Structure==
==About this Structure==
Line 35: Line 39:
[[Category: Cadherin]]
[[Category: Cadherin]]
[[Category: Strand dimer]]
[[Category: Strand dimer]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:12:24 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 17:25:46 2008''

Revision as of 14:25, 27 July 2008

Image:1zxk.png

Template:STRUCTURE 1zxk

Crystal Structure of Cadherin8 EC1 domain

Template:ABSTRACT PUBMED 16564015

About this Structure

1ZXK is a Single protein structure of sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

Type II cadherin ectodomain structures: implications for classical cadherin specificity., Patel SD, Ciatto C, Chen CP, Bahna F, Rajebhosale M, Arkus N, Schieren I, Jessell TM, Honig B, Price SR, Shapiro L, Cell. 2006 Mar 24;124(6):1255-68. PMID:16564015

Page seeded by OCA on Sun Jul 27 17:25:46 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1zxk"
Personal tools