1w8x

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[[Image:1w8x.gif|left|200px]]
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{{Seed}}
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[[Image:1w8x.png|left|200px]]
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{{STRUCTURE_1w8x| PDB=1w8x | SCENE= }}
{{STRUCTURE_1w8x| PDB=1w8x | SCENE= }}
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'''STRUCTURAL ANALYSIS OF PRD1'''
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===STRUCTURAL ANALYSIS OF PRD1===
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==Overview==
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The structure of the membrane-containing bacteriophage PRD1 has been determined by X-ray crystallography at about 4 A resolution. Here we describe the structure and location of proteins P3, P16, P30 and P31. Different structural proteins seem to have specialist roles in controlling virus assembly. The linearly extended P30 appears to nucleate the formation of the icosahedral facets (composed of trimers of the major capsid protein, P3) and acts as a molecular tape-measure, defining the size of the virus and cementing the facets together. Pentamers of P31 form the vertex base, interlocking with subunits of P3 and interacting with the membrane protein P16. The architectural similarities with adenovirus and one of the largest known virus particles PBCV-1 support the notion that the mechanism of assembly of PRD1 is scaleable and applies across the major viral lineage formed by these viruses.
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The line below this paragraph, {{ABSTRACT_PUBMED_15525981}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 15525981 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15525981}}
==About this Structure==
==About this Structure==
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[[Category: P31 penton protein]]
[[Category: P31 penton protein]]
[[Category: Virus/viral protein]]
[[Category: Virus/viral protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 13:19:17 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 17:32:21 2008''

Revision as of 14:32, 27 July 2008

Image:1w8x.png

Template:STRUCTURE 1w8x

STRUCTURAL ANALYSIS OF PRD1

Template:ABSTRACT PUBMED 15525981

About this Structure

1W8X is a Protein complex structure of sequences from Enterobacteria phage prd1. Full crystallographic information is available from OCA.

Reference

Insights into assembly from structural analysis of bacteriophage PRD1., Abrescia NG, Cockburn JJ, Grimes JM, Sutton GC, Diprose JM, Butcher SJ, Fuller SD, San Martin C, Burnett RM, Stuart DI, Bamford DH, Bamford JK, Nature. 2004 Nov 4;432(7013):68-74. PMID:15525981

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