1sty

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{{STRUCTURE_1sty| PDB=1sty | SCENE= }}
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'''THE ALPHA ANEURISM: A STRUCTURAL MOTIF REVEALED IN AN INSERTION MUTANT OF STAPHYLOCOCCAL NUCLEASE'''
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===THE ALPHA ANEURISM: A STRUCTURAL MOTIF REVEALED IN AN INSERTION MUTANT OF STAPHYLOCOCCAL NUCLEASE===
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==Overview==
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The x-ray crystal structure of a mutant of staphylococcal nuclease that contains a single glycine residue inserted in the C-terminal alpha-helix has been solved to 1.67 A resolution and refined to a crystallographic R value of 0.170. This inserted glycine residue is accommodated in the alpha-helix by formation of a previously uncharacterized bulge, which we term the alpha aneurism. A conformational search of known protein structures has identified the alpha aneurism in a number of protein families, including the histocompatibility antigens and hemoglobins.
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(as it appears on PubMed at http://www.pubmed.gov), where 8475069 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8475069}}
==About this Structure==
==About this Structure==
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[[Category: Keefe, L J.]]
[[Category: Keefe, L J.]]
[[Category: Lattman, E E.]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 17:52:08 2008''

Revision as of 14:52, 27 July 2008

Image:1sty.png

Template:STRUCTURE 1sty

THE ALPHA ANEURISM: A STRUCTURAL MOTIF REVEALED IN AN INSERTION MUTANT OF STAPHYLOCOCCAL NUCLEASE

Template:ABSTRACT PUBMED 8475069

About this Structure

1STY is a Single protein structure of sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.

Reference

The alpha aneurism: a structural motif revealed in an insertion mutant of staphylococcal nuclease., Keefe LJ, Sondek J, Shortle D, Lattman EE, Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3275-9. PMID:8475069

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