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364d

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{{STRUCTURE_364d| PDB=364d | SCENE= }}
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'''3.0 A STRUCTURE OF FRAGMENT I FROM E. COLI 5S RRNA'''
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===3.0 A STRUCTURE OF FRAGMENT I FROM E. COLI 5S RRNA===
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==Overview==
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Two new RNA structures portray how non-Watson-Crick base pairs and metal ions can produce a unique RNA shape suitable for recognition by proteins. The crystal structures of a 62 nt domain of E. coli 5S ribosomal RNA and a duplex dodecamer encompassing an internal loop E have been determined at 3.0 and 1.5 A, respectively. This loop E region is distorted by three "cross-strand purine stacks" and three novel, water-mediated noncanonical base pairs and stabilized by a four metal ion zipper. These features give its minor groove a unique hydrogen-bonding surface and make the adjacent major groove wide enough to permit recognition by the ribosomal protein L25, which is expected to bind to this surface.
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(as it appears on PubMed at http://www.pubmed.gov), where 9393863 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9393863}}
==About this Structure==
==About this Structure==
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[[Category: Overhanging base]]
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[[Category: U-rna]]
[[Category: U-rna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 20:17:24 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 18:00:21 2008''

Revision as of 15:00, 27 July 2008

Image:364d.png

Template:STRUCTURE 364d

3.0 A STRUCTURE OF FRAGMENT I FROM E. COLI 5S RRNA

Template:ABSTRACT PUBMED 9393863

About this Structure

This structure supersedes the now removed PDB entry 356d. Full crystallographic information is available from OCA.

Reference

Metals, motifs, and recognition in the crystal structure of a 5S rRNA domain., Correll CC, Freeborn B, Moore PB, Steitz TA, Cell. 1997 Nov 28;91(5):705-12. PMID:9393863

Page seeded by OCA on Sun Jul 27 18:00:21 2008

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