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1qvv

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[[Image:1qvv.gif|left|200px]]
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{{STRUCTURE_1qvv| PDB=1qvv | SCENE= }}
{{STRUCTURE_1qvv| PDB=1qvv | SCENE= }}
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'''Crystal structure of the S. cerevisiae YDR533c protein'''
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===Crystal structure of the S. cerevisiae YDR533c protein===
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==Overview==
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The ORF YDR533c from Saccharomyces cerevisiae codes for a 25.5 kDa protein of unknown biochemical function. Transcriptome analysis of yeast has shown that this gene is activated in response to various stress conditions together with proteins belonging to the heat shock family. In order to clarify its biochemical function, we determined the crystal structure of YDR533c to 1.85 A resolution by the single anomalous diffraction method. The protein possesses an alpha/beta hydrolase fold and a putative Cys-His-Glu catalytic triad common to a large enzyme family containing proteases, amidotransferases, lipases, and esterases. The protein has strong structural resemblance with the E. coli Hsp31 protein and the intracellular protease I from Pyrococcus horikoshii, which are considered class I and class III members of the Hsp31 family, respectively. Detailed structural analysis strongly suggests that the YDR533c protein crystal structure is the first one of a class II member of the Hsp31 family.
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{{ABSTRACT_PUBMED_15130476}}
==About this Structure==
==About this Structure==
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[[Category: Heat shock protein]]
[[Category: Heat shock protein]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 06:45:33 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 18:43:44 2008''

Revision as of 15:43, 27 July 2008

Image:1qvv.png

Template:STRUCTURE 1qvv

Crystal structure of the S. cerevisiae YDR533c protein

Template:ABSTRACT PUBMED 15130476

About this Structure

1QVV is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

Crystal structure of the YDR533c S. cerevisiae protein, a class II member of the Hsp31 family., Graille M, Quevillon-Cheruel S, Leulliot N, Zhou CZ, de la Sierra Gallay IL, Jacquamet L, Ferrer JL, Liger D, Poupon A, Janin J, van Tilbeurgh H, Structure. 2004 May;12(5):839-47. PMID:15130476

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