1n6z

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[[Image:1n6z.gif|left|200px]]
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{{STRUCTURE_1n6z| PDB=1n6z | SCENE= }}
{{STRUCTURE_1n6z| PDB=1n6z | SCENE= }}
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'''Solution NMR Structure of Protein YML108W from Saccharomyces cerevisiae. A novel member of the split bab fold. Northeast Structural Genomics Consortium Target YT601.'''
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===Solution NMR Structure of Protein YML108W from Saccharomyces cerevisiae. A novel member of the split bab fold. Northeast Structural Genomics Consortium Target YT601.===
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==Overview==
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As part of the Northeast Structural Genomics Consortium pilot project focused on small eukaryotic proteins and protein domains, we have determined the NMR structure of the protein encoded by ORF YML108W from Saccharomyces cerevisiae. YML108W belongs to one of the numerous structural proteomics targets whose biological function is unknown. Moreover, this protein does not have sequence similarity to any other protein. The NMR structure of YML108W consists of a four-stranded beta-sheet with strand order 2143 and two alpha-helices, with an overall topology of betabetaalphabetabetaalpha. Strand beta1 runs parallel to beta4, and beta2:beta1 and beta4:beta3 pairs are arranged in an antiparallel fashion. Although this fold belongs to the split betaalphabeta family, it appears to be unique among this family; it is a novel arrangement of secondary structure, thereby expanding the universe of protein folds.
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The line below this paragraph, {{ABSTRACT_PUBMED_12717036}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 12717036 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12717036}}
==About this Structure==
==About this Structure==
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1N6Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N6Z OCA].
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1N6Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N6Z OCA].
==Reference==
==Reference==
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[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Structural proteomic]]
[[Category: Structural proteomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:10:23 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 18:46:56 2008''

Revision as of 15:47, 27 July 2008

Image:1n6z.png

Template:STRUCTURE 1n6z

Solution NMR Structure of Protein YML108W from Saccharomyces cerevisiae. A novel member of the split bab fold. Northeast Structural Genomics Consortium Target YT601.

Template:ABSTRACT PUBMED 12717036

About this Structure

1N6Z is a Single protein structure of sequence from Saccharomyces cerevisiae. Full experimental information is available from OCA.

Reference

A novel member of the split betaalphabeta fold: Solution structure of the hypothetical protein YML108W from Saccharomyces cerevisiae., Pineda-Lucena A, Liao JC, Cort JR, Yee A, Kennedy MA, Edwards AM, Arrowsmith CH, Protein Sci. 2003 May;12(5):1136-40. PMID:12717036

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