1xuo

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[[Image:1xuo.jpg|left|200px]]
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{{STRUCTURE_1xuo| PDB=1xuo | SCENE= }}
{{STRUCTURE_1xuo| PDB=1xuo | SCENE= }}
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'''X-ray structure of LFA-1 I-domain bound to a 1,4-diazepane-2,5-dione inhibitor at 1.8A resolution'''
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===X-ray structure of LFA-1 I-domain bound to a 1,4-diazepane-2,5-dione inhibitor at 1.8A resolution===
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==Overview==
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1,4-Diazepane-2,5-diones (2) are found to be a new class of potent LFA-1 inhibitors. The synthesis, structure, and biological evaluation of these 1,4-diazepine-2,5-diones and related derivatives are described.
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(as it appears on PubMed at http://www.pubmed.gov), where 15686945 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15686945}}
==About this Structure==
==About this Structure==
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[[Category: I-domain]]
[[Category: I-domain]]
[[Category: Integrin]]
[[Category: Integrin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 15:31:52 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 19:23:53 2008''

Revision as of 16:24, 27 July 2008

Image:1xuo.png

Template:STRUCTURE 1xuo

X-ray structure of LFA-1 I-domain bound to a 1,4-diazepane-2,5-dione inhibitor at 1.8A resolution

Template:ABSTRACT PUBMED 15686945

About this Structure

1XUO is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

1,4-Diazepane-2,5-diones as novel inhibitors of LFA-1., Wattanasin S, Kallen J, Myers S, Guo Q, Sabio M, Ehrhardt C, Albert R, Hommel U, Weckbecker G, Welzenbach K, Weitz-Schmidt G, Bioorg Med Chem Lett. 2005 Feb 15;15(4):1217-20. PMID:15686945

Page seeded by OCA on Sun Jul 27 19:23:53 2008

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