1sfk

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{{STRUCTURE_1sfk| PDB=1sfk | SCENE= }}
{{STRUCTURE_1sfk| PDB=1sfk | SCENE= }}
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'''Core (C) protein from West Nile Virus, subtype Kunjin'''
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===Core (C) protein from West Nile Virus, subtype Kunjin===
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==Overview==
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We have determined the crystal structure of the core (C) protein from the Kunjin subtype of West Nile virus (WNV), closely related to the NY99 strain of WNV, currently a major health threat in the U.S. WNV is a member of the Flaviviridae family of enveloped RNA viruses that contains many important human pathogens. The C protein is associated with the RNA genome and forms the internal core which is surrounded by the envelope in the virion. The C protein structure contains four alpha helices and forms dimers that are organized into tetramers. The tetramers form extended filamentous ribbons resembling the stacked alpha helices seen in HEAT protein structures.
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(as it appears on PubMed at http://www.pubmed.gov), where 15242592 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15242592}}
==About this Structure==
==About this Structure==
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[[Category: Wang, S.]]
[[Category: Wang, S.]]
[[Category: Alpha helix]]
[[Category: Alpha helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 08:38:19 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 19:49:51 2008''

Revision as of 16:49, 27 July 2008

Image:1sfk.png

Template:STRUCTURE 1sfk

Core (C) protein from West Nile Virus, subtype Kunjin

Template:ABSTRACT PUBMED 15242592

About this Structure

1SFK is a Single protein structure of sequence from Kunjin virus. Full crystallographic information is available from OCA.

Reference

West Nile virus core protein; tetramer structure and ribbon formation., Dokland T, Walsh M, Mackenzie JM, Khromykh AA, Ee KH, Wang S, Structure. 2004 Jul;12(7):1157-63. PMID:15242592

Page seeded by OCA on Sun Jul 27 19:49:51 2008

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