1nw2

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{{STRUCTURE_1nw2| PDB=1nw2 | SCENE= }}
{{STRUCTURE_1nw2| PDB=1nw2 | SCENE= }}
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'''The crystal structure of the mutant R82E of Thioredoxin from Alicyclobacillus acidocaldarius'''
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===The crystal structure of the mutant R82E of Thioredoxin from Alicyclobacillus acidocaldarius===
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==Overview==
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We report a crystallographic and computational analysis of two mutant forms of the Alicyclobacillus acidocaldarius thioredoxin (BacTrx) done in order to evaluate the contribution of two specific amino acids to the thermostability of BacTrx. Our results suggest that the thermostability of BacTrx may be modulated by mutations affecting the overall electrostatic energy of the protein.
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{{ABSTRACT_PUBMED_12837806}}
==About this Structure==
==About this Structure==
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[[Category: Thermostability]]
[[Category: Thermostability]]
[[Category: Thioredoxin]]
[[Category: Thioredoxin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 03:02:49 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 20:18:04 2008''

Revision as of 17:18, 27 July 2008

Template:STRUCTURE 1nw2

The crystal structure of the mutant R82E of Thioredoxin from Alicyclobacillus acidocaldarius

Template:ABSTRACT PUBMED 12837806

About this Structure

1NW2 is a Single protein structure of sequence from Alicyclobacillus acidocaldarius. Full crystallographic information is available from OCA.

Reference

An integrated structural and computational study of the thermostability of two thioredoxin mutants from Alicyclobacillus acidocaldarius., Bartolucci S, De Simone G, Galdiero S, Improta R, Menchise V, Pedone C, Pedone E, Saviano M, J Bacteriol. 2003 Jul;185(14):4285-9. PMID:12837806

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