1w3z

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{{STRUCTURE_1w3z| PDB=1w3z | SCENE= }}
{{STRUCTURE_1w3z| PDB=1w3z | SCENE= }}
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'''SEMET DERIVATIVE OF BBCRASP-1 FROM BORRELIA BURGDORFERI'''
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===SEMET DERIVATIVE OF BBCRASP-1 FROM BORRELIA BURGDORFERI===
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==Overview==
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Borrelia burgdorferi, a spirochete transmitted to human hosts during feeding of infected Ixodes ticks, is the causative agent of Lyme disease. Serum-resistant B. burgdorferi strains cause a chronic, multisystemic form of the disease and bind complement factor H (FH) and FH-like protein 1 (FHL-1) on the spirochete surface. Here we report the atomic structure for the key FHL-1- and FH-binding protein BbCRASP-1 and reveal a homodimer that presents a novel target for drug design.
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(as it appears on PubMed at http://www.pubmed.gov), where 15711564 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15711564}}
==About this Structure==
==About this Structure==
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[[Category: Selenomethionine]]
[[Category: Selenomethionine]]
[[Category: Tick]]
[[Category: Tick]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 13:07:39 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 20:26:56 2008''

Revision as of 17:26, 27 July 2008

Image:1w3z.png

Template:STRUCTURE 1w3z

SEMET DERIVATIVE OF BBCRASP-1 FROM BORRELIA BURGDORFERI

Template:ABSTRACT PUBMED 15711564

About this Structure

1W3Z is a Single protein structure of sequence from Borrelia burgdorferi. Full crystallographic information is available from OCA.

Reference

A novel fold for the factor H-binding protein BbCRASP-1 of Borrelia burgdorferi., Cordes FS, Roversi P, Kraiczy P, Simon MM, Brade V, Jahraus O, Wallis R, Skerka C, Zipfel PF, Wallich R, Lea SM, Nat Struct Mol Biol. 2005 Mar;12(3):276-7. Epub 2005 Feb 13. PMID:15711564

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