1uta

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1uta.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1uta.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1uta| PDB=1uta | SCENE= }}
{{STRUCTURE_1uta| PDB=1uta | SCENE= }}
-
'''SOLUTION STRUCTURE OF THE C-TERMINAL RNP DOMAIN FROM THE DIVISOME PROTEIN FTSN'''
+
===SOLUTION STRUCTURE OF THE C-TERMINAL RNP DOMAIN FROM THE DIVISOME PROTEIN FTSN===
-
==Overview==
+
<!--
-
Prokaryotic cell division occurs through the formation of a septum, which in Escherichia coli requires coordination of the invagination of the inner membrane, biosynthesis of peptidoglycan and constriction of the outer membrane. FtsN is an essential cell division protein and forms part of the divisome, a putative complex of proteins located in the cytoplasmic membrane. Structural analyses of FtsN by nuclear magnetic resonance (NMR) reveals an RNP-like fold at the C-terminus (comprising residues 243-319), which has significant sequence homology to a peptidoglycan-binding domain. Sequential deletion mutagenesis in combination with NMR shows that the remaining of the periplasmic region of FtsN is unfolded, with the exception of three short, only partially formed helices following the trans-membrane helix. Based on these findings we propose a model in which FtsN, anchored in the inner membrane, bridges over to the peptidoglycan layer, thereby enabling the coordination of the divisome and the murein-shaping machinery in the periplasm.
+
The line below this paragraph, {{ABSTRACT_PUBMED_15101973}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 15101973 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_15101973}}
==About this Structure==
==About this Structure==
-
1UTA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UTA OCA].
+
1UTA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UTA OCA].
==Reference==
==Reference==
Line 33: Line 37:
[[Category: Rnp domain]]
[[Category: Rnp domain]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 11:39:33 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 21:35:17 2008''

Revision as of 18:35, 27 July 2008

Image:1uta.png

Template:STRUCTURE 1uta

SOLUTION STRUCTURE OF THE C-TERMINAL RNP DOMAIN FROM THE DIVISOME PROTEIN FTSN

Template:ABSTRACT PUBMED 15101973

About this Structure

1UTA is a Single protein structure of sequence from Escherichia coli. Full experimental information is available from OCA.

Reference

Solution structure and domain architecture of the divisome protein FtsN., Yang JC, Van Den Ent F, Neuhaus D, Brevier J, Lowe J, Mol Microbiol. 2004 May;52(3):651-60. PMID:15101973

Page seeded by OCA on Sun Jul 27 21:35:17 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1uta"
Personal tools