1r6j

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{{STRUCTURE_1r6j| PDB=1r6j | SCENE= }}
{{STRUCTURE_1r6j| PDB=1r6j | SCENE= }}
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'''Ultrahigh resolution Crystal Structure of syntenin PDZ2'''
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===Ultrahigh resolution Crystal Structure of syntenin PDZ2===
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==Overview==
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The crystal structure of the second PDZ domain of the scaffolding protein syntenin was solved using data extending to 0.73 A resolution. The crystallographic model, including the hydrogen atoms and the anisotropic displacement parameters, was refined to a conventional R-factor of 7.5% and Rfree of 8.7%, making it the most precise crystallographic model of a protein molecule to date. The model reveals discrete disorder in several places in the molecule, and significant plasticity of the peptide bond, with some omega angles deviating by nearly 20 degrees from planarity. Most hydrogen atoms are easily identifiable in the electron density and weak hydrogen bonds of the C-H...O type are clearly visible between the beta-strands. The study sets a new standard for high-resolution protein crystallography.
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{{ABSTRACT_PUBMED_15081807}}
==About this Structure==
==About this Structure==
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[[Category: Kang, B S.]]
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[[Category: Pdz]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 07:08:33 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 22:02:42 2008''

Revision as of 19:02, 27 July 2008

Image:1r6j.png

Template:STRUCTURE 1r6j

Ultrahigh resolution Crystal Structure of syntenin PDZ2

Template:ABSTRACT PUBMED 15081807

About this Structure

1R6J is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

The PDZ2 domain of syntenin at ultra-high resolution: bridging the gap between macromolecular and small molecule crystallography., Kang BS, Devedjiev Y, Derewenda U, Derewenda ZS, J Mol Biol. 2004 Apr 30;338(3):483-93. PMID:15081807

Page seeded by OCA on Sun Jul 27 22:02:42 2008

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