This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1jwt

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1jwt.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1jwt.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1jwt| PDB=1jwt | SCENE= }}
{{STRUCTURE_1jwt| PDB=1jwt | SCENE= }}
-
'''CRYSTAL STRUCTURE OF THROMBIN IN COMPLEX WITH A NOVEL BICYCLIC LACTAM INHIBITOR'''
+
===CRYSTAL STRUCTURE OF THROMBIN IN COMPLEX WITH A NOVEL BICYCLIC LACTAM INHIBITOR===
-
==Overview==
+
<!--
-
Peptidomimetic inhibitors of thrombin lacking the important Ser195-carbonyl interaction have been prepared. The binding energy lost after the removal of the activated carbonyl was recaptured through a series of modifications of the P1 residues of the bicyclic lactam inhibitors. Selected substituted compounds displayed useful pharmacological profiles both in vitro and in vivo.
+
The line below this paragraph, {{ABSTRACT_PUBMED_11720865}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 11720865 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_11720865}}
==About this Structure==
==About this Structure==
Line 33: Line 37:
[[Category: Winocour, P D.]]
[[Category: Winocour, P D.]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 22:01:19 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:08:30 2008''

Revision as of 20:08, 27 July 2008

Template:STRUCTURE 1jwt

CRYSTAL STRUCTURE OF THROMBIN IN COMPLEX WITH A NOVEL BICYCLIC LACTAM INHIBITOR

Template:ABSTRACT PUBMED 11720865

About this Structure

1JWT is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Novel bicyclic lactam inhibitors of thrombin: potency and selectivity optimization through P1 residues., Levesque S, St-Denis Y, Bachand B, Preville P, Leblond L, Winocour PD, Edmunds JJ, Rubin JR, Siddiqui MA, Bioorg Med Chem Lett. 2001 Dec 17;11(24):3161-4. PMID:11720865

Page seeded by OCA on Sun Jul 27 23:08:30 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools