3bqp

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{{STRUCTURE_3bqp| PDB=3bqp | SCENE= }}
{{STRUCTURE_3bqp| PDB=3bqp | SCENE= }}
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'''Crystal Structure of Human Saposin D (orthorhombic)'''
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===Crystal Structure of Human Saposin D (orthorhombic)===
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==Overview==
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Saposin D is a sphingolipid activator protein required for the lysosomal breakdown of ceramide to a fatty acid and sphingosine by acid ceramidase. The crystal structure of saposin D has been determined in two different crystal forms, resulting in a total of six crystallographically independent views of this small 80-amino-acid protein. All of the structures are highly similar and reveal the monomeric form of the saposin fold previously seen in the crystal structures of saposins A and C. Saposin D is slightly more compact than the related saposins A and C owing to a slight repositioning of the ;stem' and ;hairpin' regions of the protein.
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(as it appears on PubMed at http://www.pubmed.gov), where 18453694 is the PubMed ID number.
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{{ABSTRACT_PUBMED_18453694}}
==About this Structure==
==About this Structure==
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[[Category: Sphingolipid activator protein]]
[[Category: Sphingolipid activator protein]]
[[Category: Sphingolipid metabolism]]
[[Category: Sphingolipid metabolism]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu May 22 22:35:30 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:20:28 2008''

Revision as of 20:20, 27 July 2008

Template:STRUCTURE 3bqp

Crystal Structure of Human Saposin D (orthorhombic)

Template:ABSTRACT PUBMED 18453694

About this Structure

3BQP is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Structures of the human ceramide activator protein saposin D., Popovic K, Prive GG, Acta Crystallogr D Biol Crystallogr. 2008 May;64(Pt 5):589-94. Epub 2008, Apr 19. PMID:18453694

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