1nz8

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{{STRUCTURE_1nz8| PDB=1nz8 | SCENE= }}
{{STRUCTURE_1nz8| PDB=1nz8 | SCENE= }}
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'''Solution Structure of the N-utilisation substance G (NusG) N-terminal (NGN) domain from Thermus thermophilus'''
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===Solution Structure of the N-utilisation substance G (NusG) N-terminal (NGN) domain from Thermus thermophilus===
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==Overview==
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NusG is an essential bacterial protein modulator of transcriptional elongation and termination events, and interacts directly with RNA polymerase and Rho protein. Found also in Archaea, NusG shows stretches of sequence similarity to the eukaryotic transcription elongation factor Spt5. Herein, the three-dimensional solution structure of the bacterial NusG from Thermus thermophilus, which shows 43% amino acid sequence similarity to the Escherichia coli NusG, is described, and a survey of NusG and Spt5 amino acid sequences is presented. Although there is a clear evolutionary and functional relationship between these proteins, it is evident from the structural, sequence, and biochemical data that their binding specificities to both nucleic acids and other proteins differ.
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{{ABSTRACT_PUBMED_15162485}}
==About this Structure==
==About this Structure==
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1NZ8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZ8 OCA].
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1NZ8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZ8 OCA].
==Reference==
==Reference==
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[[Category: Termination]]
[[Category: Termination]]
[[Category: Transcription elongation]]
[[Category: Transcription elongation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:31:37 2008''

Revision as of 20:31, 27 July 2008

Image:1nz8.png

Template:STRUCTURE 1nz8

Solution Structure of the N-utilisation substance G (NusG) N-terminal (NGN) domain from Thermus thermophilus

Template:ABSTRACT PUBMED 15162485

About this Structure

1NZ8 is a Single protein structure of sequence from Thermus thermophilus. Full experimental information is available from OCA.

Reference

Structural and sequence comparisons arising from the solution structure of the transcription elongation factor NusG from Thermus thermophilus., Reay P, Yamasaki K, Terada T, Kuramitsu S, Shirouzu M, Yokoyama S, Proteins. 2004 Jul 1;56(1):40-51. PMID:15162485

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