1nko

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[[Image:1nko.gif|left|200px]]
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{{Seed}}
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{{STRUCTURE_1nko| PDB=1nko | SCENE= }}
{{STRUCTURE_1nko| PDB=1nko | SCENE= }}
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'''Energetic and structural basis of sialylated oligosaccharide recognition by the natural killer cell inhibitory receptor p75/AIRM1 or Siglec-7'''
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===Energetic and structural basis of sialylated oligosaccharide recognition by the natural killer cell inhibitory receptor p75/AIRM1 or Siglec-7===
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==Overview==
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The high-resolution crystal structure of the functional N-terminal domain from the extracellular region of the human natural killer cell inhibitory receptor p75/AIRM1 or Siglec-7 has been determined at 1.45 A resolution; it was obtained from a crystal belonging to a primitive monoclinic space group, with unit-cell parameters a = 32.65, b = 49.72, c = 39.79 A, alpha = gamma = 90, beta = 113 degrees. The structure reported here belongs to a different space group than the previously described Siglec-7 structure and was obtained using a bacterial expression system. The structure unveils the fine structural requirements adopted by a natural killer cell inhibitory receptor of the Siglec family in target-cell recognition and binding.
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The line below this paragraph, {{ABSTRACT_PUBMED_14747738}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 14747738 is the PubMed ID number.
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{{ABSTRACT_PUBMED_14747738}}
==About this Structure==
==About this Structure==
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[[Category: Immunoglobulin]]
[[Category: Immunoglobulin]]
[[Category: Siglec7]]
[[Category: Siglec7]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:38:43 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:46:11 2008''

Revision as of 20:46, 27 July 2008

Image:1nko.png

Template:STRUCTURE 1nko

Energetic and structural basis of sialylated oligosaccharide recognition by the natural killer cell inhibitory receptor p75/AIRM1 or Siglec-7

Template:ABSTRACT PUBMED 14747738

About this Structure

1NKO is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Structure of the saccharide-binding domain of the human natural killer cell inhibitory receptor p75/AIRM1., Dimasi N, Moretta A, Moretta L, Biassoni R, Mariuzza RA, Acta Crystallogr D Biol Crystallogr. 2004 Feb;60(Pt 2):401-3. Epub 2004, Jan 23. PMID:14747738

Page seeded by OCA on Sun Jul 27 23:46:11 2008

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