1nih

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[[Image:1nih.gif|left|200px]]
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{{STRUCTURE_1nih| PDB=1nih | SCENE= }}
{{STRUCTURE_1nih| PDB=1nih | SCENE= }}
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'''Structure of deoxy-quaternary haemoglobin with liganded beta subunits'''
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===Structure of deoxy-quaternary haemoglobin with liganded beta subunits===
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==Overview==
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We have determined the structure of a T-state haemoglobin in which the haem groups of the beta subunits have carbon monoxide bound, and the alpha subunits have nickel replacing the haem iron and are ligand-free. The structural adjustments on binding ligand in the T state are in the same direction as those associated with the quaternary transition, and a translational shift of the haem is severely restricted. We explain how these observations may account for the low ligand affinity of the beta haem of T-state haemoglobin.
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The line below this paragraph, {{ABSTRACT_PUBMED_2370669}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 2370669 is the PubMed ID number.
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{{ABSTRACT_PUBMED_2370669}}
==About this Structure==
==About this Structure==
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[[Category: Luisi, B.]]
[[Category: Luisi, B.]]
[[Category: Oxygen transport]]
[[Category: Oxygen transport]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:34:31 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 00:45:05 2008''

Revision as of 21:45, 27 July 2008

Image:1nih.png

Template:STRUCTURE 1nih

Structure of deoxy-quaternary haemoglobin with liganded beta subunits

Template:ABSTRACT PUBMED 2370669

About this Structure

1NIH is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Structure of deoxy-quaternary haemoglobin with liganded beta subunits., Luisi B, Liddington B, Fermi G, Shibayama N, J Mol Biol. 1990 Jul 5;214(1):7-14. PMID:2370669

Page seeded by OCA on Mon Jul 28 00:45:05 2008

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