2q8k

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{{STRUCTURE_2q8k| PDB=2q8k | SCENE= }}
{{STRUCTURE_2q8k| PDB=2q8k | SCENE= }}
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'''The crystal structure of Ebp1'''
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===The crystal structure of Ebp1===
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==Overview==
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The ErbB-3 receptor binding protein (Ebp1) is a member of the proliferation-associated 2G4 (PA2G4) family implicated in regulation of cell growth and differentiation. Here, we report the crystal structure of the human Ebp1 at 1.6 A resolution. The protein has the conserved pita bread fold of methionine aminopeptidases, but without the characteristic enzymatic activity. Moreover, Ebp1 is known to interact with a number of proteins and RNAs involved in either transcription regulation or translation control. The structure provides insights in how Ebp1 discriminates between its different interaction partners.
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(as it appears on PubMed at http://www.pubmed.gov), where 17765895 is the PubMed ID number.
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{{ABSTRACT_PUBMED_17765895}}
==About this Structure==
==About this Structure==
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 14:32:11 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 01:07:59 2008''

Revision as of 22:08, 27 July 2008

Template:STRUCTURE 2q8k

The crystal structure of Ebp1

Template:ABSTRACT PUBMED 17765895

About this Structure

2Q8K is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

The crystal structure of Ebp1 reveals a methionine aminopeptidase fold as binding platform for multiple interactions., Kowalinski E, Bange G, Bradatsch B, Hurt E, Wild K, Sinning I, FEBS Lett. 2007 Sep 18;581(23):4450-4. Epub 2007 Aug 27. PMID:17765895

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