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2gzq

From Proteopedia

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{{STRUCTURE_2gzq| PDB=2gzq | SCENE= }}
{{STRUCTURE_2gzq| PDB=2gzq | SCENE= }}
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'''Phosphatidylethanolamine-binding protein from Plasmodium vivax'''
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===Phosphatidylethanolamine-binding protein from Plasmodium vivax===
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==Overview==
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The structure of a putative Raf kinase inhibitor protein (RKIP) homolog from the eukaryotic parasite Plasmodium vivax has been studied to a resolution of 1.3 A using multiple-wavelength anomalous diffraction at the Se K edge. This protozoan protein is topologically similar to previously studied members of the phosphatidylethanolamine-binding protein (PEBP) sequence family, but exhibits a distinctive left-handed alpha-helical region at one side of the canonical phospholipid-binding site. Re-examination of previously determined PEBP structures suggests that the P. vivax protein and yeast carboxypeptidase Y inhibitor may represent a structurally distinct subfamily of the diverse PEBP-sequence family.
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{{ABSTRACT_PUBMED_17329808}}
==About this Structure==
==About this Structure==
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[[Category: Structural genomic]]
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[[Category: Structural genomics of pathogenic protozoa consortium]]
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Revision as of 22:20, 27 July 2008

Image:2gzq.png

Template:STRUCTURE 2gzq

Phosphatidylethanolamine-binding protein from Plasmodium vivax

Template:ABSTRACT PUBMED 17329808

About this Structure

2GZQ is a Single protein structure of sequence from Plasmodium vivax. Full crystallographic information is available from OCA.

Reference

The structure of Plasmodium vivax phosphatidylethanolamine-binding protein suggests a functional motif containing a left-handed helix., Arakaki T, Neely H, Boni E, Mueller N, Buckner FS, Van Voorhis WC, Lauricella A, DeTitta G, Luft J, Hol WG, Merritt EA, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Mar 1;63(Pt, 3):178-82. Epub 2007 Feb 23. PMID:17329808

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