208d

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:208d.gif|left|200px]]
+
{{Seed}}
 +
[[Image:208d.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_208d| PDB=208d | SCENE= }}
{{STRUCTURE_208d| PDB=208d | SCENE= }}
-
'''HIGH-RESOLUTION STRUCTURE OF A DNA HELIX FORMING (C.G)*G BASE TRIPLETS'''
+
===HIGH-RESOLUTION STRUCTURE OF A DNA HELIX FORMING (C.G)*G BASE TRIPLETS===
-
==Overview==
+
<!--
-
Triple helices result from interaction between single- and double-stranded nucleic acids. Their formation is a possible mechanism for recombination of homologous gene sequences in nature and provides, inter alia, a basis for artificial control of gene activity. Triple-helix motifs have been extensively studied by a variety of techniques, but few high-resolution structural data are available. The only triplet structures characterized so far by X-ray diffraction were in protein-DNA complexes studied at about 3 A resolution. We report here the X-ray analysis of a DNA nonamer, d(GCGAATTCG), to a resolution of 2.05 A, in which the extended crystal structure contains (C.G)*G triplets as a fragment of triple helix. The guanosine-containing chains are in a parallel orientation. This arrangement is a necessary feature of models for homologous recombination which results ultimately in replacement of one length of DNA by another of similar sequence. The present-structure agrees with many published predictions of triplex organization, and provides an accurate representation of an element that allows sequence-specific association between single- and double-stranded nucleic acids.
+
The line below this paragraph, {{ABSTRACT_PUBMED_7715732}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 7715732 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_7715732}}
==About this Structure==
==About this Structure==
Line 29: Line 33:
[[Category: Base triplet]]
[[Category: Base triplet]]
[[Category: Double helix]]
[[Category: Double helix]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:18:11 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 02:00:23 2008''

Revision as of 23:00, 27 July 2008

Image:208d.png

Template:STRUCTURE 208d

HIGH-RESOLUTION STRUCTURE OF A DNA HELIX FORMING (C.G)*G BASE TRIPLETS

Template:ABSTRACT PUBMED 7715732

About this Structure

Full crystallographic information is available from OCA.

Reference

High-resolution structure of a DNA helix forming (C.G)*G base triplets., Van Meervelt L, Vlieghe D, Dautant A, Gallois B, Precigoux G, Kennard O, Nature. 1995 Apr 20;374(6524):742-4. PMID:7715732

Page seeded by OCA on Mon Jul 28 02:00:23 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/208d"
Personal tools