This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1rwj

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1rwj.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1rwj.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1rwj| PDB=1rwj | SCENE= }}
{{STRUCTURE_1rwj| PDB=1rwj | SCENE= }}
-
'''c7-type three-heme cytochrome domain'''
+
===c7-type three-heme cytochrome domain===
-
==Overview==
+
<!--
-
The structure of a novel c(7)-type cytochrome domain that has two bishistidine coordinated hemes and one heme with histidine, methionine coordination (where the sixth ligand is a methionine residue) was determined at 1.7 A resolution. This domain is a representative of domains that form three polymers encoded by the Geobacter sulfurreducens genome. Two of these polymers consist of four and one protein of nine c(7)-type domains with a total of 12 and 27 hemes, respectively. Four individual domains (termed A, B, C, and D) from one such multiheme cytochrome c (ORF03300) were cloned and expressed in Escherichia coli. The domain C produced diffraction quality crystals from 2.4 M sodium malonate (pH 7). The structure was solved by MAD method and refined to an R-factor of 19.5% and R-free of 21.8%. Unlike the two c(7) molecules with known structures, one from G. sulfurreducens (PpcA) and one from Desulfuromonas acetoxidans where all three hemes are bishistidine coordinated, this domain contains a heme which is coordinated by a methionine and a histidine residue. As a result, the corresponding heme could have a higher potential than the other two hemes. The apparent midpoint reduction potential, E(app), of domain C is -105 mV, 50 mV higher than that of PpcA.
+
The line below this paragraph, {{ABSTRACT_PUBMED_15133162}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 15133162 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_15133162}}
==About this Structure==
==About this Structure==
Line 20: Line 24:
==Reference==
==Reference==
Structure of a novel c7-type three-heme cytochrome domain from a multidomain cytochrome c polymer., Pokkuluri PR, Londer YY, Duke NE, Erickson J, Pessanha M, Salgueiro CA, Schiffer M, Protein Sci. 2004 Jun;13(6):1684-92. Epub 2004 May 7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15133162 15133162]
Structure of a novel c7-type three-heme cytochrome domain from a multidomain cytochrome c polymer., Pokkuluri PR, Londer YY, Duke NE, Erickson J, Pessanha M, Salgueiro CA, Schiffer M, Protein Sci. 2004 Jun;13(6):1684-92. Epub 2004 May 7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15133162 15133162]
 +
 +
Family of cytochrome c7-type proteins from Geobacter sulfurreducens: structure of one cytochrome c7 at 1.45 A resolution., Pokkuluri PR, Londer YY, Duke NE, Long WC, Schiffer M, Biochemistry. 2004 Feb 3;43(4):849-59. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14744127 14744127]
[[Category: Geobacter sulfurreducens]]
[[Category: Geobacter sulfurreducens]]
[[Category: Single protein]]
[[Category: Single protein]]
Line 34: Line 40:
[[Category: Heme coordination in c-type cytochrome]]
[[Category: Heme coordination in c-type cytochrome]]
[[Category: Multiheme cytochrome c]]
[[Category: Multiheme cytochrome c]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 07:59:29 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 02:31:51 2008''

Revision as of 23:31, 27 July 2008

Image:1rwj.png

Template:STRUCTURE 1rwj

c7-type three-heme cytochrome domain

Template:ABSTRACT PUBMED 15133162

About this Structure

1RWJ is a Single protein structure of sequence from Geobacter sulfurreducens. Full crystallographic information is available from OCA.

Reference

Structure of a novel c7-type three-heme cytochrome domain from a multidomain cytochrome c polymer., Pokkuluri PR, Londer YY, Duke NE, Erickson J, Pessanha M, Salgueiro CA, Schiffer M, Protein Sci. 2004 Jun;13(6):1684-92. Epub 2004 May 7. PMID:15133162

Family of cytochrome c7-type proteins from Geobacter sulfurreducens: structure of one cytochrome c7 at 1.45 A resolution., Pokkuluri PR, Londer YY, Duke NE, Long WC, Schiffer M, Biochemistry. 2004 Feb 3;43(4):849-59. PMID:14744127

Page seeded by OCA on Mon Jul 28 02:31:51 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1rwj"
Personal tools