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1qf4

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{{STRUCTURE_1qf4| PDB=1qf4 | SCENE= }}
{{STRUCTURE_1qf4| PDB=1qf4 | SCENE= }}
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'''DESIGN, SYNTHESIS, AND X-RAY CRYSTAL STRUCTURE OF AN ENZYME BOUND BISUBSTRATE HYBRID INHIBITOR OF ADENYLOSUCCINATE SYNTHETASE'''
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===DESIGN, SYNTHESIS, AND X-RAY CRYSTAL STRUCTURE OF AN ENZYME BOUND BISUBSTRATE HYBRID INHIBITOR OF ADENYLOSUCCINATE SYNTHETASE===
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==Overview==
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Two relatively weak herbicides, hydantocidin phosphate and hadacidin were linked by a C(3) chain to afford a potent inhibitor (the 2S hybrid is shown) of the enzyme adenylosuccinate synthetase. The crystal structures of the bisubstrate-enzyme complexes were determined.
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(as it appears on PubMed at http://www.pubmed.gov), where 10556888 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10556888}}
==About this Structure==
==About this Structure==
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[[Category: Purine biosynthesis]]
[[Category: Purine biosynthesis]]
[[Category: Synthetase]]
[[Category: Synthetase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 06:11:22 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 03:32:36 2008''

Revision as of 00:32, 28 July 2008

Image:1qf4.png

Template:STRUCTURE 1qf4

DESIGN, SYNTHESIS, AND X-RAY CRYSTAL STRUCTURE OF AN ENZYME BOUND BISUBSTRATE HYBRID INHIBITOR OF ADENYLOSUCCINATE SYNTHETASE

Template:ABSTRACT PUBMED 10556888

About this Structure

1QF4 is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

An Enzyme-Bound Bisubstrate Hybrid Inhibitor of Adenylosuccinate Synthetase., Hanessian S, Lu PP, Sanceau JY, Chemla P, Gohda K, Fonne-Pfister R, Prade L, Cowan-Jacob SW, Angew Chem Int Ed Engl. 1999 Nov 2;38(21):3159-3162. PMID:10556888

Page seeded by OCA on Mon Jul 28 03:32:36 2008

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