2ot2

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{{STRUCTURE_2ot2| PDB=2ot2 | SCENE= }}
{{STRUCTURE_2ot2| PDB=2ot2 | SCENE= }}
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'''Solution Structure of HypC'''
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===Solution Structure of HypC===
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==Overview==
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Escherichia coli HypC plays an important role in the maturation process of the pre-maturated HycE, the large subunit of hydrogenase 3. It serves as an iron transfer as well as a chaperone protein during the maturation process of pre-HycE, and interacts with both HypD and HycE. The N-terminal cysteine residue of HypC plays a key role in the protein-protein interactions. Here, we present the three-dimensional structure of E. coli HypC, the first solution structure of HupF/HypC family. Our result demonstrates that E. coli HypC consists of a typical OB-fold beta-barrel with two C-terminal helixes. Sequence alignment and structural comparison reveal that the hydrophobic region on the surface of E. coli HypC, as well as the highly flexible C-terminal helixes, may involve in the interactions of E. coli HypC with other proteins.
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(as it appears on PubMed at http://www.pubmed.gov), where 17669368 is the PubMed ID number.
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{{ABSTRACT_PUBMED_17669368}}
==About this Structure==
==About this Structure==
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2OT2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OT2 OCA].
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2OT2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OT2 OCA].
==Reference==
==Reference==
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[[Category: Beta barrel]]
[[Category: Beta barrel]]
[[Category: Chaperone]]
[[Category: Chaperone]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 11:36:03 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 03:49:46 2008''

Revision as of 00:49, 28 July 2008

Image:2ot2.png

Template:STRUCTURE 2ot2

Solution Structure of HypC

Template:ABSTRACT PUBMED 17669368

About this Structure

2OT2 is a Single protein structure of sequence from Escherichia coli. Full experimental information is available from OCA.

Reference

Solution structure of Escherichia coli HypC., Wang L, Xia B, Jin C, Biochem Biophys Res Commun. 2007 Sep 28;361(3):665-9. Epub 2007 Jul 26. PMID:17669368

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