2qjy

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{{Seed}}
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{{STRUCTURE_2qjy| PDB=2qjy | SCENE= }}
{{STRUCTURE_2qjy| PDB=2qjy | SCENE= }}
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'''Crystal structure of rhodobacter sphaeroides double mutant with stigmatellin and UQ2'''
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===Crystal structure of rhodobacter sphaeroides double mutant with stigmatellin and UQ2===
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==Overview==
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The cytochrome bc(1) complex (bc(1)) is a major contributor to the proton motive force across the membrane by coupling electron transfer to proton translocation. The crystal structures of wild type and mutant bc(1) complexes from the photosynthetic purple bacterium Rhodobacter sphaeroides (Rsbc(1)), stabilized with the quinol oxidation (Q(P)) site inhibitor stigmatellin alone or in combination with the quinone reduction (Q(N)) site inhibitor antimycin, were determined. The high quality electron density permitted assignments of a new metal-binding site to the cytochrome c(1) subunit and a number of lipid and detergent molecules. Structural differences between Rsbc(1) and its mitochondrial counterparts are mostly extra membranous and provide a basis for understanding the function of the predominantly longer sequences in the bacterial subunits. Functional implications for the bc(1) complex are derived from analyses of 10 independent molecules in various crystal forms and from comparisons with mitochondrial complexes.
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The line below this paragraph, {{ABSTRACT_PUBMED_18039651}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 18039651 is the PubMed ID number.
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{{ABSTRACT_PUBMED_18039651}}
==About this Structure==
==About this Structure==
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[[Category: Cytochrome b]]
[[Category: Cytochrome b]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 15:05:17 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 04:29:30 2008''

Revision as of 01:30, 28 July 2008

Image:2qjy.png

Template:STRUCTURE 2qjy

Crystal structure of rhodobacter sphaeroides double mutant with stigmatellin and UQ2

Template:ABSTRACT PUBMED 18039651

About this Structure

2QJY is a Protein complex structure of sequences from Rhodobacter sphaeroides. Full crystallographic information is available from OCA.

Reference

Inhibitor-complexed Structures of the Cytochrome bc1 from the Photosynthetic Bacterium Rhodobacter sphaeroides., Esser L, Elberry M, Zhou F, Yu CA, Yu L, Xia D, J Biol Chem. 2008 Feb 1;283(5):2846-57. Epub 2007 Nov 26. PMID:18039651

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