1par

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1par.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1par.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1par| PDB=1par | SCENE= }}
{{STRUCTURE_1par| PDB=1par | SCENE= }}
-
'''DNA RECOGNITION BY BETA-SHEETS IN THE ARC REPRESSOR-OPERATOR CRYSTAL STRUCTURE'''
+
===DNA RECOGNITION BY BETA-SHEETS IN THE ARC REPRESSOR-OPERATOR CRYSTAL STRUCTURE===
-
==Overview==
+
<!--
-
Transcription of the ant gene during lytic growth of bacteriophage P22 (ref. 1) is regulated by the cooperative binding of two Arc repressor dimers to a 21-base-pair operator site. Here we report the co-crystal structure of this Arc tetramer-operator complex at 2.6 A resolution. As expected from genetic and structural studies and from the co-crystal structure of the homologous Escherichia coli MetJ repressor, each Arc dimer uses an antiparallel beta-sheet to recognize bases in the major groove. However, the Arc and MetJ complexes differ in several important ways: the beta-sheet-DNA interactions of Arc are far less symmetrical; DNA binding by Arc is accompanied by important conformational changes in the beta-sheet; and Arc uses a different part of its protein surface for dimer-dimer interactions.
+
The line below this paragraph, {{ABSTRACT_PUBMED_8107872}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 8107872 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_8107872}}
==About this Structure==
==About this Structure==
Line 28: Line 32:
[[Category: Double helix]]
[[Category: Double helix]]
[[Category: Protein-dna complex]]
[[Category: Protein-dna complex]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 04:53:24 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 05:17:57 2008''

Revision as of 02:17, 28 July 2008

Image:1par.png

Template:STRUCTURE 1par

DNA RECOGNITION BY BETA-SHEETS IN THE ARC REPRESSOR-OPERATOR CRYSTAL STRUCTURE

Template:ABSTRACT PUBMED 8107872

About this Structure

1PAR is a Single protein structure of sequence from Enterobacteria phage p22. Full crystallographic information is available from OCA.

Reference

DNA recognition by beta-sheets in the Arc repressor-operator crystal structure., Raumann BE, Rould MA, Pabo CO, Sauer RT, Nature. 1994 Feb 24;367(6465):754-7. PMID:8107872

Page seeded by OCA on Mon Jul 28 05:17:57 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1par"
Personal tools