1tqx

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[[Image:1tqx.gif|left|200px]]
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{{STRUCTURE_1tqx| PDB=1tqx | SCENE= }}
{{STRUCTURE_1tqx| PDB=1tqx | SCENE= }}
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'''Crystal Structure of Pfal009167 A Putative D-Ribulose 5-Phosphate 3-Epimerase from P.falciparum'''
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===Crystal Structure of Pfal009167 A Putative D-Ribulose 5-Phosphate 3-Epimerase from P.falciparum===
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==Overview==
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The crystal structure of Pfal009167AAA, a putative ribulose 5-phosphate 3-epimerase (PfalRPE) from Plasmodium falciparum, has been determined to 2 A resolution. RPE represents an exciting potential drug target for developing antimalarials because it is involved in the shikimate and the pentose phosphate pathways. The structure is a classic TIM-barrel fold. A coordinated Zn ion and a bound sulfate ion in the active site of the enzyme allow for a greater understanding of the mechanism of action of this enzyme. This structure is solved in the framework of the Structural Genomics of Pathogenic Protozoa (SGPP) consortium.
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(as it appears on PubMed at http://www.pubmed.gov), where 16304640 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16304640}}
==About this Structure==
==About this Structure==
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[[Category: Structural genomics of pathogenic protozoa consortium]]
[[Category: Structural genomics of pathogenic protozoa consortium]]
[[Category: Tim barrel]]
[[Category: Tim barrel]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 05:42:23 2008''

Revision as of 02:42, 28 July 2008

Image:1tqx.png

Template:STRUCTURE 1tqx

Crystal Structure of Pfal009167 A Putative D-Ribulose 5-Phosphate 3-Epimerase from P.falciparum

Template:ABSTRACT PUBMED 16304640

About this Structure

1TQX is a Single protein structure of sequence from Plasmodium falciparum 3d7. Full crystallographic information is available from OCA.

Reference

Structure of a ribulose 5-phosphate 3-epimerase from Plasmodium falciparum., Caruthers J, Bosch J, Buckner F, Van Voorhis W, Myler P, Worthey E, Mehlin C, Boni E, DeTitta G, Luft J, Lauricella A, Kalyuzhniy O, Anderson L, Zucker F, Soltis M, Hol WG, Proteins. 2006 Feb 1;62(2):338-42. PMID:16304640

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