2bkm

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2bkm.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:2bkm.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2bkm| PDB=2bkm | SCENE= }}
{{STRUCTURE_2bkm| PDB=2bkm | SCENE= }}
-
'''CRYSTAL STRUCTURE OF THE TRUNCATED HEMOGLOBIN FROM GEOBACILLUS STEAROTHERMOPHILUS'''
+
===CRYSTAL STRUCTURE OF THE TRUNCATED HEMOGLOBIN FROM GEOBACILLUS STEAROTHERMOPHILUS===
-
==Overview==
+
<!--
-
A novel truncated hemoglobin has been identified in the thermophilic bacterium Geobacillus stearothermophilus (Gs-trHb). The protein has been expressed in Escherichia coli, the 3D crystal structure (at 1.5 Angstroms resolution) and the ligand binding properties have been determined. The distal heme pocket displays an array of hydrogen bonding donors to the iron-bound ligands, including Tyr-B10 on one side of the heme pocket and Trp-G8 indole nitrogen on the opposite side. At variance with the highly similar Bacillus subtilis hemoglobin, Gs-trHb is dimeric both in the crystal and in solution and displays several unique structural properties. In the crystal cell, the iron-bound ligand is not homogeneously distributed within each distal site such that oxygen and an acetate anion can be resolved with relative occupancies of 50% each. Accordingly, equilibrium titrations of the oxygenated derivative in solution with acetate anion yield a partially saturated ferric acetate adduct. Moreover, the asymmetric unit contains two subunits and sedimentation velocity ultracentrifugation data confirm that the protein is dimeric.
+
The line below this paragraph, {{ABSTRACT_PUBMED_17126283}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 17126283 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_17126283}}
==About this Structure==
==About this Structure==
Line 31: Line 35:
[[Category: Oxygen transport]]
[[Category: Oxygen transport]]
[[Category: Transport]]
[[Category: Transport]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 20:25:18 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 06:02:06 2008''

Revision as of 03:02, 28 July 2008

Image:2bkm.png

Template:STRUCTURE 2bkm

CRYSTAL STRUCTURE OF THE TRUNCATED HEMOGLOBIN FROM GEOBACILLUS STEAROTHERMOPHILUS

Template:ABSTRACT PUBMED 17126283

About this Structure

2BKM is a Single protein structure of sequence from Geobacillus stearothermophilus. Full crystallographic information is available from OCA.

Reference

Crystal structure and ligand binding properties of the truncated hemoglobin from Geobacillus stearothermophilus., Ilari A, Kjelgaard P, von Wachenfeldt C, Catacchio B, Chiancone E, Boffi A, Arch Biochem Biophys. 2007 Jan 1;457(1):85-94. Epub 2006 Oct 30. PMID:17126283

Page seeded by OCA on Mon Jul 28 06:02:06 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2bkm"
Personal tools