1z9b

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1z9b.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1z9b.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1z9b| PDB=1z9b | SCENE= }}
{{STRUCTURE_1z9b| PDB=1z9b | SCENE= }}
-
'''Solution structure of the C1-subdomain of Bacillus stearothermophilus translation initiation factor IF2'''
+
===Solution structure of the C1-subdomain of Bacillus stearothermophilus translation initiation factor IF2===
-
==Overview==
+
<!--
-
IF2 is one of three bacterial translation initiation factors that are conserved through all kingdoms of life. It binds the 30S and 50S ribosomal subunits, as well as fMet-tRNAf(Met). After these interactions, fMet-tRNAf(Met) is oriented to the ribosomal P-site where the first amino acid of the nascent polypeptide, formylmethionine, is presented. The C-terminal domain of Bacillus stearothermophilus IF2, which is responsible for recognition and binding of fMet-tRNAf(Met), contains two structured modules. Previously, the solution structure of the most C-terminal module, IF2-C2, has been elucidated by NMR spectroscopy and direct interactions between this subdomain and fMet-tRNAf(Met) were reported. In the present NMR study we have obtained the spectral assignment of the other module of the C-terminal domain (IF2-C1) and determined its solution structure and backbone dynamics. The IF2-C1 core forms a flattened fold consisting of a central four-stranded parallel beta-sheet flanked by three alpha-helices. Although its overall organization resembles that of subdomain III of the archaeal IF2-homolog eIF5B whose crystal structure had previously been reported, some differences of potential functional significance are evident.
+
The line below this paragraph, {{ABSTRACT_PUBMED_16081655}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 16081655 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_16081655}}
==About this Structure==
==About this Structure==
-
1Z9B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z9B OCA].
+
1Z9B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z9B OCA].
==Reference==
==Reference==
Line 30: Line 34:
[[Category: Wienk, H.]]
[[Category: Wienk, H.]]
[[Category: Protein synthesis translation intiation if2 fmet-trna nmr structure]]
[[Category: Protein synthesis translation intiation if2 fmet-trna nmr structure]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 17:20:32 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 06:10:36 2008''

Revision as of 03:10, 28 July 2008

Image:1z9b.png

Template:STRUCTURE 1z9b

Solution structure of the C1-subdomain of Bacillus stearothermophilus translation initiation factor IF2

Template:ABSTRACT PUBMED 16081655

About this Structure

1Z9B is a Single protein structure of sequence from Geobacillus stearothermophilus. Full experimental information is available from OCA.

Reference

Solution structure of the C1-subdomain of Bacillus stearothermophilus translation initiation factor IF2., Wienk H, Tomaselli S, Bernard C, Spurio R, Picone D, Gualerzi CO, Boelens R, Protein Sci. 2005 Sep;14(9):2461-8. Epub 2005 Aug 4. PMID:16081655

Page seeded by OCA on Mon Jul 28 06:10:36 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1z9b"
Personal tools