1rpq

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1rpq.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1rpq.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1rpq| PDB=1rpq | SCENE= }}
{{STRUCTURE_1rpq| PDB=1rpq | SCENE= }}
-
'''High Affinity IgE Receptor (alpha chain) Complexed with Tight-Binding E131 'zeta' Peptide from Phage Display'''
+
===High Affinity IgE Receptor (alpha chain) Complexed with Tight-Binding E131 'zeta' Peptide from Phage Display===
-
==Overview==
+
<!--
-
Two structurally distinct classes of peptides were recently identified by phage display that bind the high-affinity IgE receptor, FcepsilonRI, and block IgE binding and subsequent receptor activation. Both classes adopt highly stable structures in solution, one forming a beta hairpin, with the other forming a helical "zeta" structure. Despite these differences, the two classes bind competitively to the same site on the receptor. Structural analyses of both peptide-receptor complexes by NMR spectroscopy and/or X-ray crystallography reveal that the unrelated peptide scaffolds have nevertheless converged to present a similar three-dimensional surface to interact with FcepsilonRI and that their modes of interaction share a key feature of the IgE-FcepsilonRI complex, the proline/tryptophan sandwich.
+
The line below this paragraph, {{ABSTRACT_PUBMED_15242605}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 15242605 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_15242605}}
==About this Structure==
==About this Structure==
Line 31: Line 35:
[[Category: Yin, J P.]]
[[Category: Yin, J P.]]
[[Category: Receptor/peptide complex]]
[[Category: Receptor/peptide complex]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 07:45:58 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 06:27:50 2008''

Revision as of 03:27, 28 July 2008

Image:1rpq.png

Template:STRUCTURE 1rpq

High Affinity IgE Receptor (alpha chain) Complexed with Tight-Binding E131 'zeta' Peptide from Phage Display

Template:ABSTRACT PUBMED 15242605

About this Structure

1RPQ is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Convergent recognition of the IgE binding site on the high-affinity IgE receptor., Stamos J, Eigenbrot C, Nakamura GR, Reynolds ME, Yin J, Lowman HB, Fairbrother WJ, Starovasnik MA, Structure. 2004 Jul;12(7):1289-301. PMID:15242605

Page seeded by OCA on Mon Jul 28 06:27:50 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1rpq"
Personal tools