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2mm1

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{{STRUCTURE_2mm1| PDB=2mm1 | SCENE= }}
{{STRUCTURE_2mm1| PDB=2mm1 | SCENE= }}
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'''X-RAY CRYSTAL STRUCTURE OF A RECOMBINANT HUMAN MYOGLOBIN MUTANT AT 2.8 ANGSTROMS RESOLUTION'''
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===X-RAY CRYSTAL STRUCTURE OF A RECOMBINANT HUMAN MYOGLOBIN MUTANT AT 2.8 ANGSTROMS RESOLUTION===
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==Overview==
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We have grown crystals in trigonal space group P3(2)21 of a mutant human myoglobin, aquomet form, in which lysine at position 45 has been replaced by arginine and cysteine at position 110 has been replaced by alanine. Suitable crystals of native recombinant human myoglobin have not been obtained. We have used the molecular replacement method to determine the X-ray crystal structure of the mutant at 2.8 A resolution. At the present stage of refinement, the crystallographic R-value for the model, with tightly restrained stereochemistry, is 0.158 for 5.0 to 2.8 A data. As expected, the overall structure is quite similar to the sperm whale myoglobin structure. Arginine 45 adopts a well-ordered conformation similar to that found in aquomet sperm whale myoglobin.
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The line below this paragraph, {{ABSTRACT_PUBMED_2342104}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 2342104 is the PubMed ID number.
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{{ABSTRACT_PUBMED_2342104}}
==About this Structure==
==About this Structure==
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[[Category: Lambright, D G.]]
[[Category: Lambright, D G.]]
[[Category: Oxygen transport]]
[[Category: Oxygen transport]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 09:34:08 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 07:15:24 2008''

Revision as of 04:15, 28 July 2008

Template:STRUCTURE 2mm1

X-RAY CRYSTAL STRUCTURE OF A RECOMBINANT HUMAN MYOGLOBIN MUTANT AT 2.8 ANGSTROMS RESOLUTION

Template:ABSTRACT PUBMED 2342104

About this Structure

2MM1 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

X-ray crystal structure of a recombinant human myoglobin mutant at 2.8 A resolution., Hubbard SR, Hendrickson WA, Lambright DG, Boxer SG, J Mol Biol. 1990 May 20;213(2):215-8. PMID:2342104

Page seeded by OCA on Mon Jul 28 07:15:24 2008

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