2cxc

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2cxc.gif|left|200px]]
+
{{Seed}}
 +
[[Image:2cxc.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2cxc| PDB=2cxc | SCENE= }}
{{STRUCTURE_2cxc| PDB=2cxc | SCENE= }}
-
'''Crystal structure of archaeal transcription termination factor NusA'''
+
===Crystal structure of archaeal transcription termination factor NusA===
-
==Overview==
+
<!--
-
The transcription factor NusA functions in transcriptional regulation involving termination in bacteria. A NusA homolog consisting of only the two KH domains is widely conserved in archaea, but its function remains unknown. We have found that Aeropyrum pernix NusA strongly binds to a certain CU-rich sequence near a termination signal. Our crystal structure of A. pernix NusA revealed that its spatial arrangement is quite similar to that of the KH domains of bacterial NusA. Thus, we consider archaeal NusA to have retained some functions of bacterial NusA, including the ssRNA-binding ability. Remarkable structural differences between archaeal and bacterial NusA exist at the interface with RNAP, in connection with the different NusA-binding sites around the termination signals. Transcriptional termination in archaea could differ from all of the known bacterial and eukaryal mechanisms, in terms of the combination of a bacterial factor and a eukaryal-type RNAP.
+
The line below this paragraph, {{ABSTRACT_PUBMED_17288993}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 17288993 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_17288993}}
==About this Structure==
==About this Structure==
Line 36: Line 40:
[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Transcription termination]]
[[Category: Transcription termination]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 23:16:54 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 07:25:23 2008''

Revision as of 04:25, 28 July 2008

Image:2cxc.png

Template:STRUCTURE 2cxc

Crystal structure of archaeal transcription termination factor NusA

Template:ABSTRACT PUBMED 17288993

About this Structure

2CXC is a Single protein structure of sequence from Aeropyrum pernix. Full crystallographic information is available from OCA.

Reference

Crystal structure and RNA-binding analysis of the archaeal transcription factor NusA., Shibata R, Bessho Y, Shinkai A, Nishimoto M, Fusatomi E, Terada T, Shirouzu M, Yokoyama S, Biochem Biophys Res Commun. 2007 Mar 30;355(1):122-8. Epub 2007 Jan 31. PMID:17288993

Page seeded by OCA on Mon Jul 28 07:25:23 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2cxc"
Personal tools