2zb1

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{{STRUCTURE_2zb1| PDB=2zb1 | SCENE= }}
{{STRUCTURE_2zb1| PDB=2zb1 | SCENE= }}
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'''Crystal structure of P38 in complex with biphenyl amide inhibitor'''
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===Crystal structure of P38 in complex with biphenyl amide inhibitor===
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==Overview==
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The biphenyl amides (BPAs) are a novel series of p38 MAP kinase inhibitors. The discovery of the series through structure-based focused screening is described, and the binding mode of the compounds is explained with reference to X-ray crystal structures.
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(as it appears on PubMed at http://www.pubmed.gov), where 18006306 is the PubMed ID number.
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{{ABSTRACT_PUBMED_18006306}}
==About this Structure==
==About this Structure==
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[[Category: Serine/threonine protein kinase]]
[[Category: Serine/threonine protein kinase]]
[[Category: Transferase]]
[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 20:06:20 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 07:26:09 2008''

Revision as of 04:26, 28 July 2008

Template:STRUCTURE 2zb1

Crystal structure of P38 in complex with biphenyl amide inhibitor

Template:ABSTRACT PUBMED 18006306

About this Structure

2ZB1 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Biphenyl amide p38 kinase inhibitors 1: Discovery and binding mode., Angell RM, Bamborough P, Cleasby A, Cockerill SG, Jones KL, Mooney CJ, Somers DO, Walker AL, Bioorg Med Chem Lett. 2008 Jan 1;18(1):318-23. Epub 2007 Nov 19. PMID:18006306

Page seeded by OCA on Mon Jul 28 07:26:09 2008

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