1xuq

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[[Image:1xuq.gif|left|200px]]
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{{STRUCTURE_1xuq| PDB=1xuq | SCENE= }}
{{STRUCTURE_1xuq| PDB=1xuq | SCENE= }}
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'''Crystal Structure of SodA-1 (BA4499) from Bacillus anthracis at 1.8A Resolution.'''
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===Crystal Structure of SodA-1 (BA4499) from Bacillus anthracis at 1.8A Resolution.===
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==Overview==
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The BA4499 and BA5696 genes of Bacillus anthracis encode proteins homologous to manganese superoxide dismutase, suggesting that this organism has an expanded repertoire of antioxidant proteins. Differences in metal specificity and quaternary structure between the dismutases of prokaryotes and higher eukaryotes may be exploited in the development of therapeutic antibacterial compounds. Here, the crystal structure of two Mn superoxide dismutases from B. anthracis solved to high resolution are reported. Comparison of their structures reveals that a highly conserved residue near the active centre is substituted in one of the proteins and that this is a characteristic feature of superoxide dismutases from the B. cereus/B. anthracis/B. thuringiensis group of organisms.
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(as it appears on PubMed at http://www.pubmed.gov), where 16511113 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16511113}}
==About this Structure==
==About this Structure==
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[[Category: Spine]]
[[Category: Spine]]
[[Category: Superoxide dismutase]]
[[Category: Superoxide dismutase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 15:31:53 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 08:12:09 2008''

Revision as of 05:12, 28 July 2008

Image:1xuq.png

Template:STRUCTURE 1xuq

Crystal Structure of SodA-1 (BA4499) from Bacillus anthracis at 1.8A Resolution.

Template:ABSTRACT PUBMED 16511113

About this Structure

1XUQ is a Single protein structure of sequence from Bacillus anthracis. Full crystallographic information is available from OCA.

Reference

Structures of two superoxide dismutases from Bacillus anthracis reveal a novel active centre., Boucher IW, Kalliomaa AK, Levdikov VM, Blagova EV, Fogg MJ, Brannigan JA, Wilson KS, Wilkinson AJ, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Jul 1;61(Pt, 7):621-4. Epub 2005 Jun 15. PMID:16511113

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