1n7s

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{{STRUCTURE_1n7s| PDB=1n7s | SCENE= }}
{{STRUCTURE_1n7s| PDB=1n7s | SCENE= }}
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'''High Resolution Structure of a Truncated Neuronal SNARE Complex'''
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===High Resolution Structure of a Truncated Neuronal SNARE Complex===
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==Overview==
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The structure of a truncated SNARE complex has been solved to 1.4-A resolution revealing a stabilizing salt bridge, sites of hydration, and conformational variability of the ionic central layer that were not observed in a previously published structure at 2.4-A resolution (Sutton, R. B., Fasshauer, D., Jahn, R., and Brunger, A. T. (1998) Nature 395, 347-353). The truncated complex lacks residues involved in phospholipid binding and denatures at a lower temperature than longer complexes as assessed by SDS and circular dichroism thermal melts. The truncated SNARE complex is monomeric, and it retains binding to synaptotagmin I.
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(as it appears on PubMed at http://www.pubmed.gov), where 12496247 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12496247}}
==About this Structure==
==About this Structure==
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[[Category: Four helix bundle]]
[[Category: Four helix bundle]]
[[Category: Neuronal snare protein complex]]
[[Category: Neuronal snare protein complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:12:14 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 08:28:24 2008''

Revision as of 05:28, 28 July 2008

Image:1n7s.png

Template:STRUCTURE 1n7s

High Resolution Structure of a Truncated Neuronal SNARE Complex

Template:ABSTRACT PUBMED 12496247

About this Structure

1N7S is a Protein complex structure of sequences from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

High resolution structure, stability, and synaptotagmin binding of a truncated neuronal SNARE complex., Ernst JA, Brunger AT, J Biol Chem. 2003 Mar 7;278(10):8630-6. Epub 2002 Dec 20. PMID:12496247

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