This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2oiu

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2oiu.gif|left|200px]]
+
{{Seed}}
 +
[[Image:2oiu.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2oiu| PDB=2oiu | SCENE= }}
{{STRUCTURE_2oiu| PDB=2oiu | SCENE= }}
-
'''L1 Ribozyme Ligase circular adduct'''
+
===L1 Ribozyme Ligase circular adduct===
-
==Overview==
+
<!--
-
Life originated, according to the RNA World hypothesis, from self-replicating ribozymes that catalyzed ligation of RNA fragments. We have solved the 2.6 angstrom crystal structure of a ligase ribozyme that catalyzes regiospecific formation of a 5' to 3' phosphodiester bond between the 5'-triphosphate and the 3'-hydroxyl termini of two RNA fragments. Invariant residues form tertiary contacts that stabilize a flexible stem of the ribozyme at the ligation site, where an essential magnesium ion coordinates three phosphates. The structure of the active site permits us to suggest how transition-state stabilization and a general base may catalyze the ligation reaction required for prebiotic RNA assembly.
+
The line below this paragraph, {{ABSTRACT_PUBMED_17363667}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 17363667 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_17363667}}
==About this Structure==
==About this Structure==
Line 27: Line 31:
[[Category: Ribozyme]]
[[Category: Ribozyme]]
[[Category: Rna]]
[[Category: Rna]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 11:00:21 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 08:28:23 2008''

Revision as of 05:28, 28 July 2008

Image:2oiu.png

Template:STRUCTURE 2oiu

L1 Ribozyme Ligase circular adduct

Template:ABSTRACT PUBMED 17363667

About this Structure

Full crystallographic information is available from OCA.

Reference

The structural basis of ribozyme-catalyzed RNA assembly., Robertson MP, Scott WG, Science. 2007 Mar 16;315(5818):1549-53. PMID:17363667

Page seeded by OCA on Mon Jul 28 08:28:23 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2oiu"
Personal tools